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Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy.
Marques MA, Landim-Vieira M, Moraes AH, Sun B, Johnston JR, Dieseldorff Jones KM, Cino EA, Parvatiyar MS, Valera IC, Silva JL, Galkin VE, Chase PB, Kekenes-Huskey PM, de Oliveira GAP, Pinto JR. Marques MA, et al. Among authors: galkin ve. Chem Sci. 2021 Apr 29;12(21):7308-7323. doi: 10.1039/d1sc01886h. Chem Sci. 2021. PMID: 34163821 Free PMC article.
The structure of the native cardiac thin filament at systolic Ca2+ levels.
Risi CM, Pepper I, Belknap B, Landim-Vieira M, White HD, Dryden K, Pinto JR, Chase PB, Galkin VE. Risi CM, et al. Among authors: galkin ve. Proc Natl Acad Sci U S A. 2021 Mar 30;118(13):e2024288118. doi: 10.1073/pnas.2024288118. Proc Natl Acad Sci U S A. 2021. PMID: 33753506 Free PMC article.
Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function.
Landim-Vieira M, Ma W, Song T, Rastegarpouyani H, Gong H, Coscarella IL, Bogaards SJP, Conijn SP, Ottenheijm CAC, Hwang HS, Papadaki M, Knollmann BC, Sadayappan S, Irving TC, Galkin VE, Chase PB, Pinto JR. Landim-Vieira M, et al. Among authors: galkin ve. Proc Natl Acad Sci U S A. 2023 Jun 6;120(23):e2221244120. doi: 10.1073/pnas.2221244120. Epub 2023 May 30. Proc Natl Acad Sci U S A. 2023. PMID: 37252999 Free PMC article.
Actomyosin Complex.
Pepper I, Galkin VE. Pepper I, et al. Among authors: galkin ve. Subcell Biochem. 2022;99:421-470. doi: 10.1007/978-3-031-00793-4_14. Subcell Biochem. 2022. PMID: 36151385 Free PMC article.
76 results