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Intranasal guanosine administration presents a wide therapeutic time window to reduce brain damage induced by permanent ischemia in rats.
Ramos DB, Muller GC, Rocha GB, Dellavia GH, Almeida RF, Pettenuzzo LF, Loureiro SO, Hansel G, Horn ÂC, Souza DO, Ganzella M. Ramos DB, et al. Among authors: ganzella m. Purinergic Signal. 2016 Mar;12(1):149-59. doi: 10.1007/s11302-015-9489-9. Epub 2015 Dec 23. Purinergic Signal. 2016. PMID: 26695181 Free PMC article.
Systemic administration of GMP induces anxiolytic-like behavior in rats.
Almeida RF, Cereser VH Jr, Faraco RB, Böhmer AE, Souza DO, Ganzella M. Almeida RF, et al. Among authors: ganzella m. Pharmacol Biochem Behav. 2010 Sep;96(3):306-11. doi: 10.1016/j.pbb.2010.05.022. Epub 2010 Jun 1. Pharmacol Biochem Behav. 2010. PMID: 20566406 Free article.
Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion.
Ganzella M, de Oliveira ED, Comassetto DD, Cechetti F, Cereser VH Jr, Moreira JD, Hansel G, Almeida RF, Ramos DB, Figueredo YN, Souza DG, Oses JP, Worm PV, Achaval M, Netto CA, Souza DO. Ganzella M, et al. Neurol Sci. 2012 Oct;33(5):985-97. doi: 10.1007/s10072-011-0872-1. Epub 2011 Dec 14. Neurol Sci. 2012. PMID: 22167652
Amnesic effect of GMP depends on its conversion to guanosine.
Saute JA, da Silveira LE, Soares FA, Martini LH, Souza DO, Ganzella M. Saute JA, et al. Among authors: ganzella m. Neurobiol Learn Mem. 2006 May;85(3):206-12. doi: 10.1016/j.nlm.2005.10.006. Epub 2005 Dec 1. Neurobiol Learn Mem. 2006. PMID: 16325434
Effects of depressive-like behavior of rats on brain glutamate uptake.
Almeida RF, Thomazi AP, Godinho GF, Saute JA, Wofchuk ST, Souza DO, Ganzella M. Almeida RF, et al. Among authors: ganzella m. Neurochem Res. 2010 Aug;35(8):1164-71. doi: 10.1007/s11064-010-0169-4. Epub 2010 Apr 20. Neurochem Res. 2010. PMID: 20405205
35 results