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Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis.
Vujkovic M, Keaton JM, Lynch JA, Miller DR, Zhou J, Tcheandjieu C, Huffman JE, Assimes TL, Lorenz K, Zhu X, Hilliard AT, Judy RL, Huang J, Lee KM, Klarin D, Pyarajan S, Danesh J, Melander O, Rasheed A, Mallick NH, Hameed S, Qureshi IH, Afzal MN, Malik U, Jalal A, Abbas S, Sheng X, Gao L, Kaestner KH, Susztak K, Sun YV, DuVall SL, Cho K, Lee JS, Gaziano JM, Phillips LS, Meigs JB, Reaven PD, Wilson PW, Edwards TL, Rader DJ, Damrauer SM, O'Donnell CJ, Tsao PS; HPAP Consortium; Regeneron Genetics Center; VA Million Veteran Program; Chang KM, Voight BF, Saleheen D. Vujkovic M, et al. Among authors: gao l. Nat Genet. 2020 Jul;52(7):680-691. doi: 10.1038/s41588-020-0637-y. Epub 2020 Jun 15. Nat Genet. 2020. PMID: 32541925 Free PMC article.
α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody-positive individuals.
Doliba NM, Rozo AV, Roman J, Qin W, Traum D, Gao L, Liu J, Manduchi E, Liu C, Golson ML, Vahedi G, Naji A, Matschinsky FM, Atkinson MA, Powers AC, Brissova M, Kaestner KH, Stoffers DA; HPAP Consortium. Doliba NM, et al. Among authors: gao l. J Clin Invest. 2022 Jun 1;132(11):e156243. doi: 10.1172/JCI156243. J Clin Invest. 2022. PMID: 35642629 Free PMC article.
Adaptation to chronic ER stress enforces pancreatic β-cell plasticity.
Chen CW, Guan BJ, Alzahrani MR, Gao Z, Gao L, Bracey S, Wu J, Mbow CA, Jobava R, Haataja L, Zalavadia AH, Schaffer AE, Lee H, LaFramboise T, Bederman I, Arvan P, Mathews CE, Gerling IC, Kaestner KH, Tirosh B, Engin F, Hatzoglou M. Chen CW, et al. Among authors: gao z, gao l. Nat Commun. 2022 Aug 8;13(1):4621. doi: 10.1038/s41467-022-32425-7. Nat Commun. 2022. PMID: 35941159 Free PMC article.
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