Garcia-Calvo M - Search Results

1

The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites.

Kisselev AF, Garcia-Calvo M, Overkleeft HS, Peterson E, Pennington MW, Ploegh HL, Thornberry NA, Goldberg AL. Kisselev AF, et al. J Biol Chem. 2003 Sep 19;278(38):35869-77. doi: 10.1074/jbc.M303725200. Epub 2003 Jun 18. J Biol Chem. 2003. PMID: 12815064 Free article.

2

Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway.

Casciola-Rosen L, Garcia-Calvo M, Bull HG, Becker JW, Hines T, Thornberry NA, Rosen A. Casciola-Rosen L, et al. J Biol Chem. 2007 Feb 16;282(7):4545-4552. doi: 10.1074/jbc.M606564200. Epub 2006 Dec 19. J Biol Chem. 2007. PMID: 17179148 Free article.

3

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis.

Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, Houtzager VM, Nordstrom PA, Roy S, Vaillancourt JP, Chapman KT, Nicholson DW. Thornberry NA, et al. J Biol Chem. 1997 Jul 18;272(29):17907-11. doi: 10.1074/jbc.272.29.17907. J Biol Chem. 1997. PMID: 9218414 Free article.

4

Inhibition of human caspases by peptide-based and macromolecular inhibitors.

Garcia-Calvo M, Peterson EP, Leiting B, Ruel R, Nicholson DW, Thornberry NA. Garcia-Calvo M, et al. J Biol Chem. 1998 Dec 4;273(49):32608-13. doi: 10.1074/jbc.273.49.32608. J Biol Chem. 1998. PMID: 9829999 Free article.

5

Discovery of novel aspartyl ketone dipeptides as potent and selective caspase-3 inhibitors.

Han Y, Giroux A, Grimm EL, Aspiotis R, Francoeur S, Bayly CI, Mckay DJ, Roy S, Xanthoudakis S, Vaillancourt JP, Rasper DM, Tam J, Tawa P, Thornberry NA, Paterson EP, Garcia-Calvo M, Becker JW, Rotonda J, Nicholson DW, Zamboni RJ. Han Y, et al. Bioorg Med Chem Lett. 2004 Feb 9;14(3):805-8. doi: 10.1016/j.bmcl.2003.10.064. Bioorg Med Chem Lett. 2004. PMID: 14741294

6

The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1.

Rotonda J, Garcia-Calvo M, Bull HG, Geissler WM, McKeever BM, Willoughby CA, Thornberry NA, Becker JW. Rotonda J, et al. Chem Biol. 2001 Apr;8(4):357-68. doi: 10.1016/s1074-5521(01)00018-7. Chem Biol. 2001. PMID: 11325591

7

Purification and catalytic properties of human caspase family members.

Garcia-Calvo M, Peterson EP, Rasper DM, Vaillancourt JP, Zamboni R, Nicholson DW, Thornberry NA. Garcia-Calvo M, et al. Cell Death Differ. 1999 Apr;6(4):362-9. doi: 10.1038/sj.cdd.4400497. Cell Death Differ. 1999. PMID: 10381624

8

Discovery of potent, selective human granzyme B inhibitors that inhibit CTL mediated apoptosis.

Willoughby CA, Bull HG, Garcia-Calvo M, Jiang J, Chapman KT, Thornberry NA. Willoughby CA, et al. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2197-200. doi: 10.1016/s0960-894x(02)00363-3. Bioorg Med Chem Lett. 2002. PMID: 12127536

9

Antigen processing of a short viral antigen by proteasomes.

López D, Calero O, Jiménez M, García-Calvo M, Del Val M. López D, et al. J Biol Chem. 2006 Oct 13;281(41):30315-8. doi: 10.1074/jbc.M605973200. Epub 2006 Jul 21. J Biol Chem. 2006. PMID: 16861221 Free article.

10

Concerted antigen processing of a short viral antigen by human caspase-5 and -10.

López D, Jiménez M, García-Calvo M, Del Val M. López D, et al. J Biol Chem. 2011 May 13;286(19):16910-3. doi: 10.1074/jbc.M111.234658. Epub 2011 Mar 28. J Biol Chem. 2011. PMID: 21454616 Free PMC article.

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