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Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer.
Zecchini V, Madhu B, Russell R, Pértega-Gomes N, Warren A, Gaude E, Borlido J, Stark R, Ireland-Zecchini H, Rao R, Scott H, Boren J, Massie C, Asim M, Brindle K, Griffiths J, Frezza C, Neal DE, Mills IG. Zecchini V, et al. Among authors: gaude e. EMBO J. 2014 Jun 17;33(12):1365-82. doi: 10.15252/embj.201386874. Epub 2014 May 16. EMBO J. 2014. PMID: 24837709 Free PMC article.
Defects in mitochondrial metabolism and cancer.
Gaude E, Frezza C. Gaude E, et al. Cancer Metab. 2014 Jul 17;2:10. doi: 10.1186/2049-3002-2-10. eCollection 2014. Cancer Metab. 2014. PMID: 25057353 Free PMC article. Review.
The metabolic alterations of cancer cells.
Sciacovelli M, Gaude E, Hilvo M, Frezza C. Sciacovelli M, et al. Among authors: gaude e. Methods Enzymol. 2014;542:1-23. doi: 10.1016/B978-0-12-416618-9.00001-7. Methods Enzymol. 2014. PMID: 24862258 Review.
Mitochondrial Metabolism: Yin and Yang for Tumor Progression.
Valcarcel-Jimenez L, Gaude E, Torrano V, Frezza C, Carracedo A. Valcarcel-Jimenez L, et al. Among authors: gaude e. Trends Endocrinol Metab. 2017 Oct;28(10):748-757. doi: 10.1016/j.tem.2017.06.004. Trends Endocrinol Metab. 2017. PMID: 28938972 Free PMC article. Review.
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
Sciacovelli M, Gonçalves E, Johnson TI, Zecchini VR, da Costa AS, Gaude E, Drubbel AV, Theobald SJ, Abbo SR, Tran MG, Rajeeve V, Cardaci S, Foster S, Yun H, Cutillas P, Warren A, Gnanapragasam V, Gottlieb E, Franze K, Huntly B, Maher ER, Maxwell PH, Saez-Rodriguez J, Frezza C. Sciacovelli M, et al. Among authors: gaude e. Nature. 2016 Aug 31;537(7621):544-547. doi: 10.1038/nature19353. Nature. 2016. PMID: 27580029 Free PMC article.
Fumarate induces redox-dependent senescence by modifying glutathione metabolism.
Zheng L, Cardaci S, Jerby L, MacKenzie ED, Sciacovelli M, Johnson TI, Gaude E, King A, Leach JD, Edrada-Ebel R, Hedley A, Morrice NA, Kalna G, Blyth K, Ruppin E, Frezza C, Gottlieb E. Zheng L, et al. Among authors: gaude e. Nat Commun. 2015 Jan 23;6:6001. doi: 10.1038/ncomms7001. Nat Commun. 2015. PMID: 25613188 Free PMC article.
37 results