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miR-155 augments CD8+ T-cell antitumor activity in lymphoreplete hosts by enhancing responsiveness to homeostatic γc cytokines.
Ji Y, Wrzesinski C, Yu Z, Hu J, Gautam S, Hawk NV, Telford WG, Palmer DC, Franco Z, Sukumar M, Roychoudhuri R, Clever D, Klebanoff CA, Surh CD, Waldmann TA, Restifo NP, Gattinoni L. Ji Y, et al. Among authors: gautam s. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):476-81. doi: 10.1073/pnas.1422916112. Epub 2014 Dec 29. Proc Natl Acad Sci U S A. 2015. PMID: 25548153 Free PMC article.
The transcription factor c-Myb regulates CD8+ T cell stemness and antitumor immunity.
Gautam S, Fioravanti J, Zhu W, Le Gall JB, Brohawn P, Lacey NE, Hu J, Hocker JD, Hawk NV, Kapoor V, Telford WG, Gurusamy D, Yu Z, Bhandoola A, Xue HH, Roychoudhuri R, Higgs BW, Restifo NP, Bender TP, Ji Y, Gattinoni L. Gautam S, et al. Nat Immunol. 2019 Mar;20(3):337-349. doi: 10.1038/s41590-018-0311-z. Epub 2019 Feb 18. Nat Immunol. 2019. PMID: 30778251 Free PMC article.
miR-155 harnesses Phf19 to potentiate cancer immunotherapy through epigenetic reprogramming of CD8+ T cell fate.
Ji Y, Fioravanti J, Zhu W, Wang H, Wu T, Hu J, Lacey NE, Gautam S, Le Gall JB, Yang X, Hocker JD, Escobar TM, He S, Dell'Orso S, Hawk NV, Kapoor V, Telford WG, Di Croce L, Muljo SA, Zhang Y, Sartorelli V, Gattinoni L. Ji Y, et al. Among authors: gautam s. Nat Commun. 2019 May 14;10(1):2157. doi: 10.1038/s41467-019-09882-8. Nat Commun. 2019. PMID: 31089138 Free PMC article.
Generation of clinical-grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of human B-cell malignancies.
Sabatino M, Hu J, Sommariva M, Gautam S, Fellowes V, Hocker JD, Dougherty S, Qin H, Klebanoff CA, Fry TJ, Gress RE, Kochenderfer JN, Stroncek DF, Ji Y, Gattinoni L. Sabatino M, et al. Among authors: gautam s. Blood. 2016 Jul 28;128(4):519-28. doi: 10.1182/blood-2015-11-683847. Epub 2016 May 25. Blood. 2016. PMID: 27226436 Free PMC article.
Lactate dehydrogenase inhibition synergizes with IL-21 to promote CD8+ T cell stemness and antitumor immunity.
Hermans D, Gautam S, García-Cañaveras JC, Gromer D, Mitra S, Spolski R, Li P, Christensen S, Nguyen R, Lin JX, Oh J, Du N, Veenbergen S, Fioravanti J, Ebina-Shibuya R, Bleck C, Neckers LM, Rabinowitz JD, Gattinoni L, Leonard WJ. Hermans D, et al. Among authors: gautam s. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):6047-6055. doi: 10.1073/pnas.1920413117. Epub 2020 Mar 2. Proc Natl Acad Sci U S A. 2020. PMID: 32123114 Free PMC article.
Antioxidant metabolism regulates CD8+ T memory stem cell formation and antitumor immunity.
Pilipow K, Scamardella E, Puccio S, Gautam S, De Paoli F, Mazza EM, De Simone G, Polletti S, Buccilli M, Zanon V, Di Lucia P, Iannacone M, Gattinoni L, Lugli E. Pilipow K, et al. Among authors: gautam s. JCI Insight. 2018 Sep 20;3(18):e122299. doi: 10.1172/jci.insight.122299. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232291 Free PMC article.
Association between Usage of Prophylactic AYUSH Medicines and Disease Severity in COVID-19 Patients: A Retrospective Cohort Study.
Chaudhary A, Nayak D, Pandey S, Shastri V, Kamble M, Pendse V, Prajapati V, Vaidya B, Rohit H, Beedmani S, Presswala N, Patole T, Bawaskar R, Shinde V, Datta M, Rai G, Prusty U, Pal PP, Goli SP, Sahoo AR, Muraleedharan KC, Prakash P, Mahajan A, Singh A, Krishnan R, Pawaskar N, Srivastava A, Ningthoujam GD, Sadarla RK, Sonny R, Karso L, Sarkar S, Prasad S, Shrivastava AK, Kumar A, Kumar N, Raveendar C, Kumar BR, Sastry V, Dasari A, Sundeep KS, Kaushik S, Rath P, Gautam S, Shil RC, Swain TL, Reddy GRC, Pradeep S, Stevenson S, Choubey G, Debata L, Khurana A. Chaudhary A, et al. Among authors: gautam s. Homeopathy. 2024 May 7. doi: 10.1055/s-0044-1779693. Online ahead of print. Homeopathy. 2024. PMID: 38714214
1,440 results