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Elongator mutation in mice induces neurodegeneration and ataxia-like behavior.
Kojic M, Gaik M, Kiska B, Salerno-Kochan A, Hunt S, Tedoldi A, Mureev S, Jones A, Whittle B, Genovesi LA, Adolphe C, Brown DL, Stow JL, Alexandrov K, Sah P, Glatt S, Wainwright BJ. Kojic M, et al. Among authors: genovesi la. Nat Commun. 2018 Aug 10;9(1):3195. doi: 10.1038/s41467-018-05765-6. Nat Commun. 2018. PMID: 30097576 Free PMC article.
Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype.
Kojic M, Gawda T, Gaik M, Begg A, Salerno-Kochan A, Kurniawan ND, Jones A, Drożdżyk K, Kościelniak A, Chramiec-Głąbik A, Hediyeh-Zadeh S, Kasherman M, Shim WJ, Sinniah E, Genovesi LA, Abrahamsen RK, Fenger CD, Madsen CG, Cohen JS, Fatemi A, Stark Z, Lunke S, Lee J, Hansen JK, Boxill MF, Keren B, Marey I, Saenz MS, Brown K, Alexander SA, Mureev S, Batzilla A, Davis MJ, Piper M, Bodén M, Burne THJ, Palpant NJ, Møller RS, Glatt S, Wainwright BJ. Kojic M, et al. Among authors: genovesi la. Nat Commun. 2021 May 11;12(1):2678. doi: 10.1038/s41467-021-22888-5. Nat Commun. 2021. PMID: 33976153 Free PMC article.
Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma.
Genovesi LA, Millar A, Tolson E, Singleton M, Hassall E, Kojic M, Brighi C, Girard E, Andradas C, Kuchibhotla M, Bhuva DD, Endersby R, Gottardo NG, Bernard A, Adolphe C, Olson JM, Taylor MD, Davis MJ, Wainwright BJ. Genovesi LA, et al. Genome Med. 2021 Jun 21;13(1):103. doi: 10.1186/s13073-021-00920-z. Genome Med. 2021. PMID: 34154646 Free PMC article.
Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibition.
Vo T, Balderson B, Jones K, Ni G, Crawford J, Millar A, Tolson E, Singleton M, Kojic M, Robertson T, Walters S, Mulay O, Bhuva DD, Davis MJ, Wainwright BJ, Nguyen Q, Genovesi LA. Vo T, et al. Among authors: genovesi la. Genome Med. 2023 May 1;15(1):29. doi: 10.1186/s13073-023-01185-4. Genome Med. 2023. PMID: 37127652 Free PMC article.
15 results