Georgiadis MM - Search Results

1

Crystal structures of GCN2 protein kinase C-terminal domains suggest regulatory differences in yeast and mammals.

He H, Singh I, Wek SA, Dey S, Baird TD, Wek RC, Georgiadis MM. He H, et al. Among authors: georgiadis mm. J Biol Chem. 2014 May 23;289(21):15023-34. doi: 10.1074/jbc.M114.560789. Epub 2014 Apr 9. J Biol Chem. 2014. PMID: 24719324 Free PMC article.

2

Redox regulation of DNA repair: implications for human health and cancer therapeutic development.

Luo M, He H, Kelley MR, Georgiadis MM. Luo M, et al. Among authors: georgiadis mm. Antioxid Redox Signal. 2010 Jun 1;12(11):1247-69. doi: 10.1089/ars.2009.2698. Antioxid Redox Signal. 2010. PMID: 19764832 Free PMC article. Review.

3

Crystal structure of the human Hsmar1-derived transposase domain in the DNA repair enzyme Metnase.

Goodwin KD, He H, Imasaki T, Lee SH, Georgiadis MM. Goodwin KD, et al. Among authors: georgiadis mm. Biochemistry. 2010 Jul 13;49(27):5705-13. doi: 10.1021/bi100171x. Biochemistry. 2010. PMID: 20521842

4

Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease.

Luo M, Zhang J, He H, Su D, Chen Q, Gross ML, Kelley MR, Georgiadis MM. Luo M, et al. Among authors: georgiadis mm. Biochemistry. 2012 Jan 17;51(2):695-705. doi: 10.1021/bi201034z. Epub 2012 Jan 4. Biochemistry. 2012. PMID: 22148505 Free PMC article.

5

The DDN catalytic motif is required for Metnase functions in non-homologous end joining (NHEJ) repair and replication restart.

Kim HS, Chen Q, Kim SK, Nickoloff JA, Hromas R, Georgiadis MM, Lee SH. Kim HS, et al. Among authors: georgiadis mm. J Biol Chem. 2014 Apr 11;289(15):10930-10938. doi: 10.1074/jbc.M113.533216. Epub 2014 Feb 25. J Biol Chem. 2014. PMID: 24573677 Free PMC article.

6

The structure of an authentic spore photoproduct lesion in DNA suggests a basis for recognition.

Singh I, Jian Y, Li L, Georgiadis MM. Singh I, et al. Among authors: georgiadis mm. Acta Crystallogr D Biol Crystallogr. 2014 Mar;70(Pt 3):752-9. doi: 10.1107/S1399004713032987. Epub 2014 Feb 15. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 24598744 Free PMC article.

7

High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.

He H, Chen Q, Georgiadis MM. He H, et al. Among authors: georgiadis mm. Biochemistry. 2014 Oct 21;53(41):6520-9. doi: 10.1021/bi500676p. Epub 2014 Oct 8. Biochemistry. 2014. PMID: 25251148 Free PMC article.

8

Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K).

Singh I, Kim MJ, Molt RW, Hoshika S, Benner SA, Georgiadis MM. Singh I, et al. Among authors: georgiadis mm. ACS Synth Biol. 2017 Nov 17;6(11):2118-2129. doi: 10.1021/acssynbio.7b00150. Epub 2017 Aug 15. ACS Synth Biol. 2017. PMID: 28752992 Free PMC article.

9

Snapshots of an evolved DNA polymerase pre- and post-incorporation of an unnatural nucleotide.

Singh I, Laos R, Hoshika S, Benner SA, Georgiadis MM. Singh I, et al. Among authors: georgiadis mm. Nucleic Acids Res. 2018 Sep 6;46(15):7977-7988. doi: 10.1093/nar/gky552. Nucleic Acids Res. 2018. PMID: 29986111 Free PMC article.

10

"Skinny" and "Fat" DNA: Two New Double Helices.

Hoshika S, Singh I, Switzer C, Molt RW Jr, Leal NA, Kim MJ, Kim MS, Kim HJ, Georgiadis MM, Benner SA. Hoshika S, et al. Among authors: georgiadis mm. J Am Chem Soc. 2018 Sep 19;140(37):11655-11660. doi: 10.1021/jacs.8b05042. Epub 2018 Sep 10. J Am Chem Soc. 2018. PMID: 30148365

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