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Interpreting type 1 diabetes risk with genetics and single-cell epigenomics.
Nature. 2021 Jun;594(7863):398-402. doi: 10.1038/s41586-021-03552-w. Epub 2021 May 19.
Nature. 2021.
PMID: 34012112
Free PMC article.
Mutations and variants of ONECUT1 in diabetes.
Philippi A, Heller S, Costa IG, Senée V, Breunig M, Li Z, Kwon G, Russell R, Illing A, Lin Q, Hohwieler M, Degavre A, Zalloua P, Liebau S, Schuster M, Krumm J, Zhang X, Geusz R, Benthuysen JR, Wang A, Chiou J, Gaulton K, Neubauer H, Simon E, Klein T, Wagner M, Nair G, Besse C, Dandine-Roulland C, Olaso R, Deleuze JF, Kuster B, Hebrok M, Seufferlein T, Sander M, Boehm BO, Oswald F, Nicolino M, Julier C, Kleger A.
Philippi A, et al.
Nat Med. 2021 Nov;27(11):1928-1940. doi: 10.1038/s41591-021-01502-7. Epub 2021 Oct 18.
Nat Med. 2021.
PMID: 34663987
Free PMC article.
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Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development.
Geusz RJ, Wang A, Chiou J, Lancman JJ, Wetton N, Kefalopoulou S, Wang J, Qiu Y, Yan J, Aylward A, Ren B, Dong PDS, Gaulton KJ, Sander M.
Geusz RJ, et al.
Elife. 2021 Feb 5;10:e59067. doi: 10.7554/eLife.59067.
Elife. 2021.
PMID: 33544077
Free PMC article.
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Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.
Geusz RJ, Wang A, Lam DK, Vinckier NK, Alysandratos KD, Roberts DA, Wang J, Kefalopoulou S, Ramirez A, Qiu Y, Chiou J, Gaulton KJ, Ren B, Kotton DN, Sander M.
Geusz RJ, et al.
Nat Commun. 2021 Nov 17;12(1):6636. doi: 10.1038/s41467-021-26950-0.
Nat Commun. 2021.
PMID: 34789735
Free PMC article.
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Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation.
Heller S, Li Z, Lin Q, Geusz R, Breunig M, Hohwieler M, Zhang X, Nair GG, Seufferlein T, Hebrok M, Sander M, Julier C, Kleger A, Costa IG.
Heller S, et al.
Commun Biol. 2021 Nov 17;4(1):1298. doi: 10.1038/s42003-021-02818-3.
Commun Biol. 2021.
PMID: 34789845
Free PMC article.
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LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development.
Vinckier NK, Patel NA, Geusz RJ, Wang A, Wang J, Matta I, Harrington AR, Wortham M, Wetton N, Wang J, Jhala US, Rosenfeld MG, Benner CW, Shih HP, Sander M.
Vinckier NK, et al. Among authors: geusz rj.
Nat Commun. 2020 Apr 29;11(1):2082. doi: 10.1038/s41467-020-16017-x.
Nat Commun. 2020.
PMID: 32350257
Free PMC article.
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Mitigating hypoxic stress on pancreatic islets via in situ oxygen generating biomaterial.
Coronel MM, Geusz R, Stabler CL.
Coronel MM, et al.
Biomaterials. 2017 Jun;129:139-151. doi: 10.1016/j.biomaterials.2017.03.018. Epub 2017 Mar 18.
Biomaterials. 2017.
PMID: 28342320
Free PMC article.
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