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Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways.
Deelen J, Uh HW, Monajemi R, van Heemst D, Thijssen PE, Böhringer S, van den Akker EB, de Craen AJ, Rivadeneira F, Uitterlinden AG, Westendorp RG, Goeman JJ, Slagboom PE, Houwing-Duistermaat JJ, Beekman M. Deelen J, et al. Among authors: goeman jj. Age (Dordr). 2013 Feb;35(1):235-49. doi: 10.1007/s11357-011-9340-3. Epub 2011 Nov 24. Age (Dordr). 2013. PMID: 22113349 Free PMC article.
Transcriptional profiling of human familial longevity indicates a role for ASF1A and IL7R.
Passtoors WM, Boer JM, Goeman JJ, Akker EB, Deelen J, Zwaan BJ, Scarborough A, Breggen Rv, Vossen RH, Houwing-Duistermaat JJ, Ommen GJ, Westendorp RG, van Heemst D, de Craen AJ, White AJ, Gunn DA, Beekman M, Slagboom PE. Passtoors WM, et al. Among authors: goeman jj. PLoS One. 2012;7(1):e27759. doi: 10.1371/journal.pone.0027759. Epub 2012 Jan 11. PLoS One. 2012. PMID: 22247756 Free PMC article.
Different gene sets contribute to different symptom dimensions of depression and anxiety.
van Veen T, Goeman JJ, Monajemi R, Wardenaar KJ, Hartman CA, Snieder H, Nolte IM, Penninx BW, Zitman FG. van Veen T, et al. Among authors: goeman jj. Am J Med Genet B Neuropsychiatr Genet. 2012 Jul;159B(5):519-28. doi: 10.1002/ajmg.b.32058. Epub 2012 May 9. Am J Med Genet B Neuropsychiatr Genet. 2012. PMID: 22573416 Free article.
Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human aging.
van den Akker EB, Passtoors WM, Jansen R, van Zwet EW, Goeman JJ, Hulsman M, Emilsson V, Perola M, Willemsen G, Penninx BW, Heijmans BT, Maier AB, Boomsma DI, Kok JN, Slagboom PE, Reinders MJ, Beekman M. van den Akker EB, et al. Among authors: goeman jj. Aging Cell. 2014 Apr;13(2):216-25. doi: 10.1111/acel.12160. Epub 2013 Nov 19. Aging Cell. 2014. PMID: 24119000 Free PMC article.
A data-driven methodology reveals novel myofiber clusters in older human muscles.
Raz Y, van den Akker EB, Roest T, Riaz M, van de Rest O, Suchiman HED, Lakenberg N, Stassen SA, van Putten M, Feskens EJM, Reinders MJT, Goeman J, Beekman M, Raz V, Slagboom PE. Raz Y, et al. FASEB J. 2020 Apr;34(4):5525-5537. doi: 10.1096/fj.201902350R. Epub 2020 Mar 5. FASEB J. 2020. PMID: 32141137
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array.
Slieker RC, Bos SD, Goeman JJ, Bovée JV, Talens RP, van der Breggen R, Suchiman HE, Lameijer EW, Putter H, van den Akker EB, Zhang Y, Jukema JW, Slagboom PE, Meulenbelt I, Heijmans BT. Slieker RC, et al. Among authors: goeman jj. Epigenetics Chromatin. 2013 Aug 6;6(1):26. doi: 10.1186/1756-8935-6-26. Epigenetics Chromatin. 2013. PMID: 23919675 Free PMC article.
Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study.
Ramos YF, den Hollander W, Bovée JV, Bomer N, van der Breggen R, Lakenberg N, Keurentjes JC, Goeman JJ, Slagboom PE, Nelissen RG, Bos SD, Meulenbelt I. Ramos YF, et al. Among authors: goeman jj. PLoS One. 2014 Jul 23;9(7):e103056. doi: 10.1371/journal.pone.0103056. eCollection 2014. PLoS One. 2014. PMID: 25054223 Free PMC article.
Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine.
Onderwater GLJ, Ligthart L, Bot M, Demirkan A, Fu J, van der Kallen CJH, Vijfhuizen LS, Pool R, Liu J, Vanmolkot FHM, Beekman M, Wen KX, Amin N, Thesing CS, Pijpers JA, Kies DA, Zielman R, de Boer I, van Greevenbroek MMJ, Arts ICW, Milaneschi Y, Schram MT, Dagnelie PC, Franke L, Ikram MA, Ferrari MD, Goeman JJ, Slagboom PE, Wijmenga C, Stehouwer CDA, Boomsma DI, van Duijn CM, Penninx BW, 't Hoen PAC, Terwindt GM, van den Maagdenberg AMJM; BBMRI Metabolomics Consortium. Onderwater GLJ, et al. Among authors: goeman jj. Neurology. 2019 Apr 16;92(16):e1899-e1911. doi: 10.1212/WNL.0000000000007313. Epub 2019 Apr 3. Neurology. 2019. PMID: 30944236 Free PMC article.
DNA methylation signatures link prenatal famine exposure to growth and metabolism.
Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, Slieker RC, Stok AP, Thijssen PE, Müller F, van Zwet EW, Bock C, Meissner A, Lumey LH, Eline Slagboom P, Heijmans BT. Tobi EW, et al. Among authors: goeman jj. Nat Commun. 2014 Nov 26;5:5592. doi: 10.1038/ncomms6592. Nat Commun. 2014. PMID: 25424739 Free PMC article.
MicroRNA classifier and nomogram for metastasis prediction in colon cancer.
Goossens-Beumer IJ, Derr RS, Buermans HP, Goeman JJ, Böhringer S, Morreau H, Nitsche U, Janssen KP, van de Velde CJ, Kuppen PJ. Goossens-Beumer IJ, et al. Among authors: goeman jj. Cancer Epidemiol Biomarkers Prev. 2015 Jan;24(1):187-97. doi: 10.1158/1055-9965.EPI-14-0544-T. Epub 2014 Oct 14. Cancer Epidemiol Biomarkers Prev. 2015. PMID: 25315964
168 results