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Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.
Weng D, Marty-Roix R, Ganesan S, Proulx MK, Vladimer GI, Kaiser WJ, Mocarski ES, Pouliot K, Chan FK, Kelliher MA, Harris PA, Bertin J, Gough PJ, Shayakhmetov DM, Goguen JD, Fitzgerald KA, Silverman N, Lien E. Weng D, et al. Among authors: goguen jd. Proc Natl Acad Sci U S A. 2014 May 20;111(20):7391-6. doi: 10.1073/pnas.1403477111. Epub 2014 May 5. Proc Natl Acad Sci U S A. 2014. PMID: 24799678 Free PMC article.
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E. Orning P, et al. Among authors: goguen jd. Science. 2018 Nov 30;362(6418):1064-1069. doi: 10.1126/science.aau2818. Epub 2018 Oct 25. Science. 2018. PMID: 30361383 Free PMC article.
The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation.
Ratner D, Orning MP, Proulx MK, Wang D, Gavrilin MA, Wewers MD, Alnemri ES, Johnson PF, Lee B, Mecsas J, Kayagaki N, Goguen JD, Lien E. Ratner D, et al. Among authors: goguen jd. PLoS Pathog. 2016 Dec 2;12(12):e1006035. doi: 10.1371/journal.ppat.1006035. eCollection 2016 Dec. PLoS Pathog. 2016. PMID: 27911947 Free PMC article.
The NLRP12 inflammasome recognizes Yersinia pestis.
Vladimer GI, Weng D, Paquette SW, Vanaja SK, Rathinam VA, Aune MH, Conlon JE, Burbage JJ, Proulx MK, Liu Q, Reed G, Mecsas JC, Iwakura Y, Bertin J, Goguen JD, Fitzgerald KA, Lien E. Vladimer GI, et al. Among authors: goguen jd. Immunity. 2012 Jul 27;37(1):96-107. doi: 10.1016/j.immuni.2012.07.006. Immunity. 2012. PMID: 22840842 Free PMC article.
58 results