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Orai1-mediated I (CRAC) is essential for neointima formation after vascular injury.
Zhang W, Halligan KE, Zhang X, Bisaillon JM, Gonzalez-Cobos JC, Motiani RK, Hu G, Vincent PA, Zhou J, Barroso M, Singer HA, Matrougui K, Trebak M. Zhang W, et al. Among authors: gonzalez cobos jc. Circ Res. 2011 Aug 19;109(5):534-42. doi: 10.1161/CIRCRESAHA.111.246777. Epub 2011 Jul 7. Circ Res. 2011. PMID: 21737791 Free PMC article.
Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration.
Spinelli AM, González-Cobos JC, Zhang X, Motiani RK, Rowan S, Zhang W, Garrett J, Vincent PA, Matrougui K, Singer HA, Trebak M. Spinelli AM, et al. Among authors: gonzalez cobos jc. Pflugers Arch. 2012 Nov;464(5):481-92. doi: 10.1007/s00424-012-1160-5. Epub 2012 Sep 27. Pflugers Arch. 2012. PMID: 23014880 Free PMC article.
What role for store-operated Ca²⁺ entry in muscle?
Trebak M, Zhang W, Ruhle B, Henkel MM, González-Cobos JC, Motiani RK, Stolwijk JA, Newton RL, Zhang X. Trebak M, et al. Among authors: gonzalez cobos jc. Microcirculation. 2013 May;20(4):330-6. doi: 10.1111/micc.12042. Microcirculation. 2013. PMID: 23312019 Free PMC article. Review.
Store-independent Orai1/3 channels activated by intracrine leukotriene C4: role in neointimal hyperplasia.
González-Cobos JC, Zhang X, Zhang W, Ruhle B, Motiani RK, Schindl R, Muik M, Spinelli AM, Bisaillon JM, Shinde AV, Fahrner M, Singer HA, Matrougui K, Barroso M, Romanin C, Trebak M. González-Cobos JC, et al. Circ Res. 2013 Mar 29;112(7):1013-25. doi: 10.1161/CIRCRESAHA.111.300220. Epub 2013 Jan 24. Circ Res. 2013. PMID: 23349245 Free PMC article.
Mechanisms of STIM1 activation of store-independent leukotriene C4-regulated Ca2+ channels.
Zhang X, González-Cobos JC, Schindl R, Muik M, Ruhle B, Motiani RK, Bisaillon JM, Zhang W, Fahrner M, Barroso M, Matrougui K, Romanin C, Trebak M. Zhang X, et al. Among authors: gonzalez cobos jc. Mol Cell Biol. 2013 Sep;33(18):3715-23. doi: 10.1128/MCB.00554-13. Epub 2013 Jul 22. Mol Cell Biol. 2013. PMID: 23878392 Free PMC article.
TRPC channels in smooth muscle cells.
Gonzalez-Cobos JC, Trebak M. Gonzalez-Cobos JC, et al. Front Biosci (Landmark Ed). 2010 Jun 1;15(3):1023-39. doi: 10.2741/3660. Front Biosci (Landmark Ed). 2010. PMID: 20515740 Free PMC article. Review.
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