Gosker HR - Search Results

1

Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells.

Hoffmann RF, Zarrintan S, Brandenburg SM, Kol A, de Bruin HG, Jafari S, Dijk F, Kalicharan D, Kelders M, Gosker HR, Ten Hacken NH, van der Want JJ, van Oosterhout AJ, Heijink IH. Hoffmann RF, et al. Among authors: gosker hr. Respir Res. 2013 Oct 2;14(1):97. doi: 10.1186/1465-9921-14-97. Respir Res. 2013. PMID: 24088173 Free PMC article.

2

Uncoupling protein-3 content is decreased in peripheral skeletal muscle of patients with COPD.

Gosker HR, Schrauwen P, Hesselink MK, Schaart G, van der Vusse GJ, Wouters EF, Schols AM. Gosker HR, et al. Eur Respir J. 2003 Jul;22(1):88-93. doi: 10.1183/09031936.03.00089802. Eur Respir J. 2003. PMID: 12882456 Free article.

3

Reduced mitochondrial density in the vastus lateralis muscle of patients with COPD.

Gosker HR, Hesselink MK, Duimel H, Ward KA, Schols AM. Gosker HR, et al. Eur Respir J. 2007 Jul;30(1):73-9. doi: 10.1183/09031936.00146906. Epub 2007 Apr 11. Eur Respir J. 2007. PMID: 17428811 Free article.

4

Extrapulmonary manifestations of chronic obstructive pulmonary disease in a mouse model of chronic cigarette smoke exposure.

Gosker HR, Langen RC, Bracke KR, Joos GF, Brusselle GG, Steele C, Ward KA, Wouters EF, Schols AM. Gosker HR, et al. Am J Respir Cell Mol Biol. 2009 Jun;40(6):710-6. doi: 10.1165/rcmb.2008-0312OC. Epub 2008 Nov 6. Am J Respir Cell Mol Biol. 2009. PMID: 18988919

5

Loss of quadriceps muscle oxidative phenotype and decreased endurance in patients with mild-to-moderate COPD.

van den Borst B, Slot IG, Hellwig VA, Vosse BA, Kelders MC, Barreiro E, Schols AM, Gosker HR. van den Borst B, et al. Among authors: gosker hr. J Appl Physiol (1985). 2013 May;114(9):1319-28. doi: 10.1152/japplphysiol.00508.2012. Epub 2012 Jul 19. J Appl Physiol (1985). 2013. PMID: 22815389 Free article.

6

Hypoxia differentially regulates muscle oxidative fiber type and metabolism in a HIF-1α-dependent manner.

Slot IG, Schols AM, Vosse BA, Kelders MC, Gosker HR. Slot IG, et al. Among authors: gosker hr. Cell Signal. 2014 Sep;26(9):1837-45. doi: 10.1016/j.cellsig.2014.04.016. Epub 2014 May 2. Cell Signal. 2014. PMID: 24794533

7

Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition.

Eurlings IM, Reynaert NL, van den Beucken T, Gosker HR, de Theije CC, Verhamme FM, Bracke KR, Wouters EF, Dentener MA. Eurlings IM, et al. Among authors: gosker hr. PLoS One. 2014 Oct 16;9(10):e107757. doi: 10.1371/journal.pone.0107757. eCollection 2014. PLoS One. 2014. PMID: 25329389 Free PMC article.

8

Impaired exercise training-induced muscle fiber hypertrophy and Akt/mTOR pathway activation in hypoxemic patients with COPD.

Costes F, Gosker H, Feasson L, Desgeorges M, Kelders M, Castells J, Schols A, Freyssenet D. Costes F, et al. J Appl Physiol (1985). 2015 Apr 15;118(8):1040-9. doi: 10.1152/japplphysiol.00557.2014. Epub 2015 Feb 19. J Appl Physiol (1985). 2015. PMID: 25701004 Free article.

9

Increased Myogenic and Protein Turnover Signaling in Skeletal Muscle of Chronic Obstructive Pulmonary Disease Patients With Sarcopenia.

Kneppers AEM, Langen RCJ, Gosker HR, Verdijk LB, Cebron Lipovec N, Leermakers PA, Kelders MCJM, de Theije CC, Omersa D, Lainscak M, Schols AMWJ. Kneppers AEM, et al. Among authors: gosker hr. J Am Med Dir Assoc. 2017 Jul 1;18(7):637.e1-637.e11. doi: 10.1016/j.jamda.2017.04.016. Epub 2017 May 31. J Am Med Dir Assoc. 2017. PMID: 28578881

10

Molecular signalling towards mitochondrial breakdown is enhanced in skeletal muscle of patients with chronic obstructive pulmonary disease (COPD).

Leermakers PA, Schols AMWJ, Kneppers AEM, Kelders MCJM, de Theije CC, Lainscak M, Gosker HR. Leermakers PA, et al. Among authors: gosker hr. Sci Rep. 2018 Oct 9;8(1):15007. doi: 10.1038/s41598-018-33471-2. Sci Rep. 2018. PMID: 30302028 Free PMC article.

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