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Page 1
Interrogating the Genetic Determinants of Tourette's Syndrome and Other Tic Disorders Through Genome-Wide Association Studies.
Yu D, Sul JH, Tsetsos F, Nawaz MS, Huang AY, Zelaya I, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau G, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, Barr CL, Grados M, Singer HS, Nöthen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Luðvigsson P, Sæmundsen E, Thorarensen Ó, Atzmon G, Barzilai N, Wagner M, Moessner R, Ophoff R, Pato CN, Pato MT, Knowles JA, Roffman JL, Smoller JW, Buckner RL, Willsey AJ, Tischfield JA, Heiman GA, Stefansson H, Stefansson K, Posthuma D, Cox NJ, Pauls DL, Freimer NB, Neale BM, Davis LK, Paschou P, Coppola G, Mathews CA, Scharf JM; Tourette Association of America International Consortium for Genetics, the Gilles de la Tourette GWAS Replication Initiative, the Tourette International Collaborative Genetics Study, and the Psychiatric Genomics Consortium Tourette Syndrome Working Group. Yu D, et al. Among authors: grados m. Am J Psychiatry. 2019 Mar 1;176(3):217-227. doi: 10.1176/appi.ajp.2018.18070857. Am J Psychiatry. 2019. PMID: 30818990 Free PMC article.
Synaptic processes and immune-related pathways implicated in Tourette syndrome.
Tsetsos F, Yu D, Sul JH, Huang AY, Illmann C, Osiecki L, Darrow SM, Hirschtritt ME, Greenberg E, Muller-Vahl KR, Stuhrmann M, Dion Y, Rouleau GA, Aschauer H, Stamenkovic M, Schlögelhofer M, Sandor P, Barr CL, Grados MA, Singer HS, Nöthen MM, Hebebrand J, Hinney A, King RA, Fernandez TV, Barta C, Tarnok Z, Nagy P, Depienne C, Worbe Y, Hartmann A, Budman CL, Rizzo R, Lyon GJ, McMahon WM, Batterson JR, Cath DC, Malaty IA, Okun MS, Berlin C, Woods DW, Lee PC, Jankovic J, Robertson MM, Gilbert DL, Brown LW, Coffey BJ, Dietrich A, Hoekstra PJ, Kuperman S, Zinner SH, Wagner M, Knowles JA, Jeremy Willsey A, Tischfield JA, Heiman GA, Cox NJ, Freimer NB, Neale BM, Davis LK, Coppola G, Mathews CA, Scharf JM, Paschou P; Tourette Association of America International Consortium for Genetics; Barr CL, Batterson JR, Berlin C, Budman CL, Cath DC, Coppola G, Cox NJ, Darrow S, Davis LK, Dion Y, Freimer NB, Grados MA, Greenberg E, Hirschtritt ME, Huang AY, Illmann C, King RA, Kurlan R, Leckman JF, Lyon GJ, Malaty IA, Mathews CA, McMahon WM, Neale BM, Okun MS, Osiecki L, Robertson MM, Rouleau GA, Sandor P, Scharf JM, Singer HS, Smit JH, Sul JH, Yu D; Gilles de la Tourette GWAS Replicatio… See abstract for full author list ➔ Tsetsos F, et al. Among authors: grados ma. Transl Psychiatry. 2021 Jan 18;11(1):56. doi: 10.1038/s41398-020-01082-z. Transl Psychiatry. 2021. PMID: 33462189 Free PMC article.
Social disinhibition is a heritable subphenotype of tics in Tourette syndrome.
Hirschtritt ME, Darrow SM, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King RA, Pauls DL, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, McGrath LM, McMahon WM, Lee PC, Delucchi KL, Scharf JM, Mathews CA; Tourette Syndrome Association International Consortium for Genetics (TSAICG). Hirschtritt ME, et al. Among authors: grados m. Neurology. 2016 Aug 2;87(5):497-504. doi: 10.1212/WNL.0000000000002910. Epub 2016 Jul 1. Neurology. 2016. PMID: 27371487 Free PMC article.
Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome.
Darrow SM, Hirschtritt ME, Davis LK, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King R, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, McGrath LM, McMahon WM, Lee PC, Delucchi KL, Scharf JM, Mathews CA; Tourette Syndrome Association International Consortium for Genetics. Darrow SM, et al. Among authors: grados m. Am J Psychiatry. 2017 Apr 1;174(4):387-396. doi: 10.1176/appi.ajp.2016.16020240. Epub 2016 Nov 4. Am J Psychiatry. 2017. PMID: 27809572 Free PMC article.
Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome.
Huang AY, Yu D, Davis LK, Sul JH, Tsetsos F, Ramensky V, Zelaya I, Ramos EM, Osiecki L, Chen JA, McGrath LM, Illmann C, Sandor P, Barr CL, Grados M, Singer HS, Nöthen MM, Hebebrand J, King RA, Dion Y, Rouleau G, Budman CL, Depienne C, Worbe Y, Hartmann A, Müller-Vahl KR, Stuhrmann M, Aschauer H, Stamenkovic M, Schloegelhofer M, Konstantinidis A, Lyon GJ, McMahon WM, Barta C, Tarnok Z, Nagy P, Batterson JR, Rizzo R, Cath DC, Wolanczyk T, Berlin C, Malaty IA, Okun MS, Woods DW, Rees E, Pato CN, Pato MT, Knowles JA, Posthuma D, Pauls DL, Cox NJ, Neale BM, Freimer NB, Paschou P, Mathews CA, Scharf JM, Coppola G; Tourette Syndrome Association International Consortium for Genetics (TSAICG); Gilles de la Tourette Syndrome GWAS Replication Initiative (GGRI). Huang AY, et al. Among authors: grados m. Neuron. 2017 Jun 21;94(6):1101-1111.e7. doi: 10.1016/j.neuron.2017.06.010. Neuron. 2017. PMID: 28641109 Free PMC article.
Autism Spectrum Symptoms in a Tourette's Disorder Sample.
Darrow SM, Grados M, Sandor P, Hirschtritt ME, Illmann C, Osiecki L, Dion Y, King R, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, McMahon WM, Lee PC, Delucchi KL, Scharf JM, Mathews CA. Darrow SM, et al. Among authors: grados m. J Am Acad Child Adolesc Psychiatry. 2017 Jul;56(7):610-617.e1. doi: 10.1016/j.jaac.2017.05.002. Epub 2017 May 11. J Am Acad Child Adolesc Psychiatry. 2017. PMID: 28647013 Free PMC article.
Prevalence and predictors of hair pulling disorder and excoriation disorder in Tourette syndrome.
Greenberg E, Tung ES, Gauvin C, Osiecki L, Yang KG, Curley E, Essa A, Illmann C, Sandor P, Dion Y, Lyon GJ, King RA, Darrow S, Hirschtritt ME, Budman CL, Grados M, Pauls DL, Keuthen NJ, Mathews CA, Scharf JM; Tourette Association of America International Consortium for Genetics. Greenberg E, et al. Among authors: grados m. Eur Child Adolesc Psychiatry. 2018 May;27(5):569-579. doi: 10.1007/s00787-017-1074-z. Epub 2017 Nov 2. Eur Child Adolesc Psychiatry. 2018. PMID: 29098466 Free PMC article.
Elevated common variant genetic risk for tourette syndrome in a densely-affected pedigree.
Halvorsen M, Szatkiewicz J, Mudgal P, Yu D; Psychiatric Genomics Consortium TS/OCD Working Group; Nordsletten AE, Mataix-Cols D, Mathews CA, Scharf JM, Mattheisen M, Robertson MM, McQuillin A, Crowley JJ. Halvorsen M, et al. Mol Psychiatry. 2021 Dec;26(12):7522-7529. doi: 10.1038/s41380-021-01277-w. Epub 2021 Sep 15. Mol Psychiatry. 2021. PMID: 34526668 Free PMC article.
Genome-wide association study of Tourette's syndrome.
Scharf JM, Yu D, Mathews CA, Neale BM, Stewart SE, Fagerness JA, Evans P, Gamazon E, Edlund CK, Service SK, Tikhomirov A, Osiecki L, Illmann C, Pluzhnikov A, Konkashbaev A, Davis LK, Han B, Crane J, Moorjani P, Crenshaw AT, Parkin MA, Reus VI, Lowe TL, Rangel-Lugo M, Chouinard S, Dion Y, Girard S, Cath DC, Smit JH, King RA, Fernandez TV, Leckman JF, Kidd KK, Kidd JR, Pakstis AJ, State MW, Herrera LD, Romero R, Fournier E, Sandor P, Barr CL, Phan N, Gross-Tsur V, Benarroch F, Pollak Y, Budman CL, Bruun RD, Erenberg G, Naarden AL, Lee PC, Weiss N, Kremeyer B, Berrío GB, Campbell DD, Cardona Silgado JC, Ochoa WC, Mesa Restrepo SC, Muller H, Valencia Duarte AV, Lyon GJ, Leppert M, Morgan J, Weiss R, Grados MA, Anderson K, Davarya S, Singer H, Walkup J, Jankovic J, Tischfield JA, Heiman GA, Gilbert DL, Hoekstra PJ, Robertson MM, Kurlan R, Liu C, Gibbs JR, Singleton A; North American Brain Expression Consortium; Hardy J; UK Human Brain Expression Database; Strengman E, Ophoff RA, Wagner M, Moessner R, Mirel DB, Posthuma D, Sabatti C, Eskin E, Conti DV, Knowles JA, Ruiz-Linares A, Rouleau GA, Purcell S, Heutink P, Oostra BA, McMahon WM, Freimer NB, Cox NJ, Pauls DL. Scharf JM, et al. Among authors: grados ma. Mol Psychiatry. 2013 Jun;18(6):721-8. doi: 10.1038/mp.2012.69. Epub 2012 Aug 14. Mol Psychiatry. 2013. PMID: 22889924 Free PMC article.
Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome.
Hirschtritt ME, Darrow SM, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King RA, Pauls D, Budman CL, Cath DC, Greenberg E, Lyon GJ, Yu D, McGrath LM, McMahon WM, Lee PC, Delucchi KL, Scharf JM, Mathews CA. Hirschtritt ME, et al. Among authors: grados m. Psychol Med. 2018 Jan;48(2):279-293. doi: 10.1017/S0033291717001672. Epub 2017 Jun 27. Psychol Med. 2018. PMID: 28651666 Free PMC article.
169 results