Groop L - Search Results

1

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans.

Ingelsson E, Langenberg C, Hivert MF, Prokopenko I, Lyssenko V, Dupuis J, Mägi R, Sharp S, Jackson AU, Assimes TL, Shrader P, Knowles JW, Zethelius B, Abbasi FA, Bergman RN, Bergmann A, Berne C, Boehnke M, Bonnycastle LL, Bornstein SR, Buchanan TA, Bumpstead SJ, Böttcher Y, Chines P, Collins FS, Cooper CC, Dennison EM, Erdos MR, Ferrannini E, Fox CS, Graessler J, Hao K, Isomaa B, Jameson KA, Kovacs P, Kuusisto J, Laakso M, Ladenvall C, Mohlke KL, Morken MA, Narisu N, Nathan DM, Pascoe L, Payne F, Petrie JR, Sayer AA, Schwarz PE, Scott LJ, Stringham HM, Stumvoll M, Swift AJ, Syvänen AC, Tuomi T, Tuomilehto J, Tönjes A, Valle TT, Williams GH, Lind L, Barroso I, Quertermous T, Walker M, Wareham NJ, Meigs JB, McCarthy MI, Groop L, Watanabe RM, Florez JC; MAGIC investigators. Ingelsson E, et al. Among authors: groop l. Diabetes. 2010 May;59(5):1266-75. doi: 10.2337/db09-1568. Epub 2010 Feb 25. Diabetes. 2010. PMID: 20185807 Free PMC article.

2

Variants in the calpain-10 gene predispose to insulin resistance and elevated free fatty acid levels.

Orho-Melander M, Klannemark M, Svensson MK, Ridderstråle M, Lindgren CM, Groop L. Orho-Melander M, et al. Among authors: groop l. Diabetes. 2002 Aug;51(8):2658-64. doi: 10.2337/diabetes.51.8.2658. Diabetes. 2002. PMID: 12145185

3

FOXC2 mRNA Expression and a 5' untranslated region polymorphism of the gene are associated with insulin resistance.

Ridderstråle M, Carlsson E, Klannemark M, Cederberg A, Kösters C, Tornqvist H, Storgaard H, Vaag A, Enerbäck S, Groop L. Ridderstråle M, et al. Among authors: groop l. Diabetes. 2002 Dec;51(12):3554-60. doi: 10.2337/diabetes.51.12.3554. Diabetes. 2002. PMID: 12453913

4

Importance of obtaining independent measures of insulin secretion and insulin sensitivity during the same test: results with the Botnia clamp.

Tripathy D, Wessman Y, Gullström M, Tuomi T, Groop L. Tripathy D, et al. Among authors: groop l. Diabetes Care. 2003 May;26(5):1395-401. doi: 10.2337/diacare.26.5.1395. Diabetes Care. 2003. PMID: 12716795

5

A combination of human leukocyte antigen DQB1*02 and the tumor necrosis factor alpha promoter G308A polymorphism predisposes to an insulin-deficient phenotype in patients with type 2 diabetes.

Li H, Groop L, Nilsson A, Weng J, Tuomi T. Li H, et al. Among authors: groop l. J Clin Endocrinol Metab. 2003 Jun;88(6):2767-74. doi: 10.1210/jc.2002-020506. J Clin Endocrinol Metab. 2003. PMID: 12788886

6

Haplotype structure and genotype-phenotype correlations of the sulfonylurea receptor and the islet ATP-sensitive potassium channel gene region.

Florez JC, Burtt N, de Bakker PI, Almgren P, Tuomi T, Holmkvist J, Gaudet D, Hudson TJ, Schaffner SF, Daly MJ, Hirschhorn JN, Groop L, Altshuler D. Florez JC, et al. Among authors: groop l. Diabetes. 2004 May;53(5):1360-8. doi: 10.2337/diabetes.53.5.1360. Diabetes. 2004. PMID: 15111507

7

Cosegregation of MIDD and MODY in a pedigree: functional and clinical consequences.

Cervin C, Liljeström B, Tuomi T, Heikkinen S, Tapanainen JS, Groop L, Cilio CM. Cervin C, et al. Among authors: groop l. Diabetes. 2004 Jul;53(7):1894-9. doi: 10.2337/diabetes.53.7.1894. Diabetes. 2004. PMID: 15220216

8

Contribution of insulin-stimulated glucose uptake and basal hepatic insulin sensitivity to surrogate measures of insulin sensitivity.

Tripathy D, Almgren P, Tuomi T, Groop L. Tripathy D, et al. Among authors: groop l. Diabetes Care. 2004 Sep;27(9):2204-10. doi: 10.2337/diacare.27.9.2204. Diabetes Care. 2004. PMID: 15333485

9

Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes.

Florez JC, Sjögren M, Burtt N, Orho-Melander M, Schayer S, Sun M, Almgren P, Lindblad U, Tuomi T, Gaudet D, Hudson TJ, Daly MJ, Ardlie KG, Hirschhorn JN, Altshuler D, Groop L. Florez JC, et al. Among authors: groop l. Diabetes. 2004 Dec;53(12):3313-8. doi: 10.2337/diabetes.53.12.3313. Diabetes. 2004. PMID: 15561965

10

Predictors of and longitudinal changes in insulin sensitivity and secretion preceding onset of type 2 diabetes.

Lyssenko V, Almgren P, Anevski D, Perfekt R, Lahti K, Nissén M, Isomaa B, Forsen B, Homström N, Saloranta C, Taskinen MR, Groop L, Tuomi T; Botnia study group. Lyssenko V, et al. Among authors: groop l. Diabetes. 2005 Jan;54(1):166-74. doi: 10.2337/diabetes.54.1.166. Diabetes. 2005. PMID: 15616025

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