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Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS.
Andlauer TFM, Link J, Martin D, Ryner M, Hermanrud C, Grummel V, Auer M, Hegen H, Aly L, Gasperi C, Knier B, Müller-Myhsok B, Jensen PEH, Sellebjerg F, Kockum I, Olsson T, Pallardy M, Spindeldreher S, Deisenhammer F, Fogdell-Hahn A, Hemmer B; ABIRISK consortium. Andlauer TFM, et al. Among authors: grummel v. BMC Med. 2020 Nov 4;18(1):298. doi: 10.1186/s12916-020-01769-6. BMC Med. 2020. PMID: 33143745 Free PMC article.
HLA-DRB1*0401 and HLA-DRB1*0408 are strongly associated with the development of antibodies against interferon-beta therapy in multiple sclerosis.
Hoffmann S, Cepok S, Grummel V, Lehmann-Horn K, Hackermüller J, Stadler PF, Hartung HP, Berthele A, Deisenhammer F, Wassmuth R, Hemmer B. Hoffmann S, et al. Among authors: grummel v. Am J Hum Genet. 2008 Aug;83(2):219-27. doi: 10.1016/j.ajhg.2008.07.006. Epub 2008 Jul 24. Am J Hum Genet. 2008. PMID: 18656179 Free PMC article.
35 results