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A second, non-canonical RNA-dependent RNA polymerase in SARS coronavirus.
Imbert I, Guillemot JC, Bourhis JM, Bussetta C, Coutard B, Egloff MP, Ferron F, Gorbalenya AE, Canard B. Imbert I, et al. Among authors: guillemot jc. EMBO J. 2006 Oct 18;25(20):4933-42. doi: 10.1038/sj.emboj.7601368. Epub 2006 Oct 5. EMBO J. 2006. PMID: 17024178 Free PMC article.
Identification of allosteric inhibitors blocking the hepatitis C virus polymerase NS5B in the RNA synthesis initiation step.
Betzi S, Eydoux C, Bussetta C, Blemont M, Leyssen P, Debarnot C, Ben-Rahou M, Haiech J, Hibert M, Gueritte F, Grierson DS, Romette JL, Guillemot JC, Neyts J, Alvarez K, Morelli X, Dutartre H, Canard B. Betzi S, et al. Among authors: guillemot jc. Antiviral Res. 2009 Oct;84(1):48-59. doi: 10.1016/j.antiviral.2009.06.009. Epub 2009 Jul 7. Antiviral Res. 2009. PMID: 19589358
The flavivirus polymerase as a target for drug discovery.
Malet H, Massé N, Selisko B, Romette JL, Alvarez K, Guillemot JC, Tolou H, Yap TL, Vasudevan S, Lescar J, Canard B. Malet H, et al. Among authors: guillemot jc. Antiviral Res. 2008 Oct;80(1):23-35. doi: 10.1016/j.antiviral.2008.06.007. Epub 2008 Jul 9. Antiviral Res. 2008. PMID: 18611413 Review.
Molecular mapping of the RNA Cap 2'-O-methyltransferase activation interface between severe acute respiratory syndrome coronavirus nsp10 and nsp16.
Lugari A, Betzi S, Decroly E, Bonnaud E, Hermant A, Guillemot JC, Debarnot C, Borg JP, Bouvet M, Canard B, Morelli X, Lécine P. Lugari A, et al. Among authors: guillemot jc. J Biol Chem. 2010 Oct 22;285(43):33230-33241. doi: 10.1074/jbc.M110.120014. Epub 2010 Aug 10. J Biol Chem. 2010. PMID: 20699222 Free PMC article.
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Shannon A, Fattorini V, Sama B, Selisko B, Feracci M, Falcou C, Gauffre P, El Kazzi P, Delpal A, Decroly E, Alvarez K, Eydoux C, Guillemot JC, Moussa A, Good SS, La Colla P, Lin K, Sommadossi JP, Zhu Y, Yan X, Shi H, Ferron F, Canard B. Shannon A, et al. Among authors: guillemot jc. Nat Commun. 2022 Feb 2;13(1):621. doi: 10.1038/s41467-022-28113-1. Nat Commun. 2022. PMID: 35110538 Free PMC article.
Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives.
Coutard B, Barral K, Lichière J, Selisko B, Martin B, Aouadi W, Lombardia MO, Debart F, Vasseur JJ, Guillemot JC, Canard B, Decroly E. Coutard B, et al. Among authors: guillemot jc. J Virol. 2017 Feb 14;91(5):e02202-16. doi: 10.1128/JVI.02202-16. Print 2017 Mar 1. J Virol. 2017. PMID: 28031359 Free PMC article.
111 results