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New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation.
Fabbri C, Tansey KE, Perlis RH, Hauser J, Henigsberg N, Maier W, Mors O, Placentino A, Rietschel M, Souery D, Breen G, Curtis C, Sang-Hyuk L, Newhouse S, Patel H, Guipponi M, Perroud N, Bondolfi G, O'Donovan M, Lewis G, Biernacka JM, Weinshilboum RM, Farmer A, Aitchison KJ, Craig I, McGuffin P, Uher R, Lewis CM. Fabbri C, et al. Among authors: guipponi m. Pharmacogenomics J. 2018 May 22;18(3):413-421. doi: 10.1038/tpj.2017.44. Epub 2017 Nov 21. Pharmacogenomics J. 2018. PMID: 29160301 Free PMC article.
Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project.
Perroud N, Uher R, Ng MY, Guipponi M, Hauser J, Henigsberg N, Maier W, Mors O, Gennarelli M, Rietschel M, Souery D, Dernovsek MZ, Stamp AS, Lathrop M, Farmer A, Breen G, Aitchison KJ, Lewis CM, Craig IW, McGuffin P. Perroud N, et al. Among authors: guipponi m. Pharmacogenomics J. 2012 Feb;12(1):68-77. doi: 10.1038/tpj.2010.70. Epub 2010 Sep 28. Pharmacogenomics J. 2012. PMID: 20877300 Clinical Trial.
Copy number variants and therapeutic response to antidepressant medication in major depressive disorder.
Tansey KE, Rucker JJ, Kavanagh DH, Guipponi M, Perroud N, Bondolfi G, Domenici E, Evans DM, Hauser J, Henigsberg N, Jerman B, Maier W, Mors O, O'Donovan M, Peters TJ, Placentino A, Rietschel M, Souery D, Aitchison KJ, Craig I, Farmer A, Wendland JR, Malafosse A, Lewis G, Kapur S, McGuffin P, Uher R. Tansey KE, et al. Among authors: guipponi m. Pharmacogenomics J. 2014 Aug;14(4):395-9. doi: 10.1038/tpj.2013.51. Epub 2014 Jan 21. Pharmacogenomics J. 2014. PMID: 24445990
Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis.
Tansey KE, Guipponi M, Perroud N, Bondolfi G, Domenici E, Evans D, Hall SK, Hauser J, Henigsberg N, Hu X, Jerman B, Maier W, Mors O, O'Donovan M, Peters TJ, Placentino A, Rietschel M, Souery D, Aitchison KJ, Craig I, Farmer A, Wendland JR, Malafosse A, Holmans P, Lewis G, Lewis CM, Stensbøl TB, Kapur S, McGuffin P, Uher R. Tansey KE, et al. Among authors: guipponi m. PLoS Med. 2012;9(10):e1001326. doi: 10.1371/journal.pmed.1001326. Epub 2012 Oct 16. PLoS Med. 2012. PMID: 23091423 Free PMC article.
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.
Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJ, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S; Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium (Corporate Collaborator); Martin NG, Medland SE, Metspalu A, Milani L, Noethen MM, Potash JB, Rietschel M, Rietveld CA, Ripke S, Shi J; Social Science Genetic Association Consortium Corporate Collaborator; Willemsen G, Zhu Z, Boomsma DI, Wray NR, Penninx BW; Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium Corporate Collaborator; Social Science Genetic Association Consortium Corporate Collaborator. Peyrot WJ, et al. Mol Psychiatry. 2015 Jun;20(6):735-43. doi: 10.1038/mp.2015.50. Epub 2015 Apr 28. Mol Psychiatry. 2015. PMID: 25917368 Free PMC article.
Contribution of common genetic variants to antidepressant response.
Tansey KE, Guipponi M, Hu X, Domenici E, Lewis G, Malafosse A, Wendland JR, Lewis CM, McGuffin P, Uher R. Tansey KE, et al. Among authors: guipponi m. Biol Psychiatry. 2013 Apr 1;73(7):679-82. doi: 10.1016/j.biopsych.2012.10.030. Epub 2012 Dec 11. Biol Psychiatry. 2013. PMID: 23237317
A mega-analysis of genome-wide association studies for major depressive disorder.
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium; Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, Müller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O'Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigurdsson E, … See abstract for full author list ➔ Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, et al. Among authors: guipponi m. Mol Psychiatry. 2013 Apr;18(4):497-511. doi: 10.1038/mp.2012.21. Epub 2012 Apr 3. Mol Psychiatry. 2013. PMID: 22472876 Free PMC article.
Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders.
Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Conley ED; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC); Ruepp A, Müller-Myhsok B, Hariri AR, Binder EB; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium PGC. Arloth J, et al. Neuron. 2015 Jun 3;86(5):1189-202. doi: 10.1016/j.neuron.2015.05.034. Neuron. 2015. PMID: 26050039 Free PMC article.
112 results