Tetrahydroprotoberberine alkaloids with dopamine and σ receptor affinity.
Gadhiya S, Madapa S, Kurtzman T, Alberts IL, Ramsey S, Pillarsetty NK, Kalidindi T, Harding WW.
Gadhiya S, et al.
Bioorg Med Chem. 2016 May 1;24(9):2060-71. doi: 10.1016/j.bmc.2016.03.037. Epub 2016 Mar 21.
Bioorg Med Chem. 2016.
PMID: 27032890
Free PMC article.
Two series of analogues of the tetrahydroprotoberberine (THPB) alkaloid ()-stepholidine that (a) contain various alkoxy substituents at the C10 position and, (b) were de-rigidified with respect to ()-stepholidine, were synthesized and evaluated for affinity at dopamine and sigma …
Two series of analogues of the tetrahydroprotoberberine (THPB) alkaloid ()-stepholidine that (a) contain various alkoxy substituents at the …