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Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase.
Mitchell J, Paul P, Chen HJ, Morris A, Payling M, Falchi M, Habgood J, Panoutsou S, Winkler S, Tisato V, Hajitou A, Smith B, Vance C, Shaw C, Mazarakis ND, de Belleroche J. Mitchell J, et al. Among authors: habgood j. Proc Natl Acad Sci U S A. 2010 Apr 20;107(16):7556-61. doi: 10.1073/pnas.0914128107. Epub 2010 Apr 5. Proc Natl Acad Sci U S A. 2010. PMID: 20368421 Free PMC article.
Copper, zinc superoxide dismutase (SOD1) and its role in neuronal function and disease with particular relevance to motor neurone disease/amyotrophic lateral sclerosis.
de Belleroche J, Orrell RW, Virgo L, Habgood J, Gardiner IM, Malaspina A, Kaushik N, Mitchell J, Greenwood J. de Belleroche J, et al. Among authors: habgood j. Biochem Soc Trans. 1998 Aug;26(3):476-80. doi: 10.1042/bst0260476. Biochem Soc Trans. 1998. PMID: 9765899 Review. No abstract available.
Clinical and functional investigation of 10 missense mutations and a novel frameshift insertion mutation of the gene for copper-zinc superoxide dismutase in UK families with amyotrophic lateral sclerosis.
Orrell RW, Habgood JJ, Gardiner I, King AW, Bowe FA, Hallewell RA, Marklund SL, Greenwood J, Lane RJ, deBelleroche J. Orrell RW, et al. Among authors: habgood jj. Neurology. 1997 Mar;48(3):746-51. doi: 10.1212/wnl.48.3.746. Neurology. 1997. PMID: 9065559
A locus on chromosome 9p confers susceptibility to ALS and frontotemporal dementia.
Morita M, Al-Chalabi A, Andersen PM, Hosler B, Sapp P, Englund E, Mitchell JE, Habgood JJ, de Belleroche J, Xi J, Jongjaroenprasert W, Horvitz HR, Gunnarsson LG, Brown RH Jr. Morita M, et al. Among authors: habgood jj. Neurology. 2006 Mar 28;66(6):839-44. doi: 10.1212/01.wnl.0000200048.53766.b4. Epub 2006 Jan 18. Neurology. 2006. PMID: 16421333
25 results