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Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J, Han B, Park YR, Raychaudhuri S, Pouget JG, Hübenthal M, Folseraas T, Wang Y, Esko T, Metspalu A, Westra HJ, Franke L, Pers TH, Weersma RK, Collij V, D'Amato M, Halfvarson J, Jensen AB, Lieb W, Degenhardt F, Forstner AJ, Hofmann A; International IBD Genetics Consortium (IIBDGC); International Genetics of Ankylosing Spondylitis Consortium (IGAS); International PSC Study Group (IPSCSG); Genetic Analysis of Psoriasis Consortium (GAPC); Psoriasis Association Genetics Extension (PAGE); Schreiber S, Mrowietz U, Juran BD, Lazaridis KN, Brunak S, Dale AM, Trembath RC, Weidinger S, Weichenthal M, Ellinghaus E, Elder JT, Barker JN, Andreassen OA, McGovern DP, Karlsen TH, Barrett JC, Parkes M, Brown MA, Franke A. Ellinghaus D, et al. Among authors: han b. Nat Genet. 2016 May;48(5):510-8. doi: 10.1038/ng.3528. Epub 2016 Mar 14. Nat Genet. 2016. PMID: 26974007 Free PMC article.
Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.
Han B, Diogo D, Eyre S, Kallberg H, Zhernakova A, Bowes J, Padyukov L, Okada Y, González-Gay MA, Rantapää-Dahlqvist S, Martin J, Huizinga TW, Plenge RM, Worthington J, Gregersen PK, Klareskog L, de Bakker PI, Raychaudhuri S. Han B, et al. Am J Hum Genet. 2014 Apr 3;94(4):522-32. doi: 10.1016/j.ajhg.2014.02.013. Epub 2014 Mar 20. Am J Hum Genet. 2014. PMID: 24656864 Free PMC article.
Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations.
Okada Y, Kim K, Han B, Pillai NE, Ong RT, Saw WY, Luo M, Jiang L, Yin J, Bang SY, Lee HS, Brown MA, Bae SC, Xu H, Teo YY, de Bakker PI, Raychaudhuri S. Okada Y, et al. Among authors: han b. Hum Mol Genet. 2014 Dec 20;23(25):6916-26. doi: 10.1093/hmg/ddu387. Epub 2014 Jul 28. Hum Mol Genet. 2014. PMID: 25070946 Free PMC article.
Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes.
Okada Y, Han B, Tsoi LC, Stuart PE, Ellinghaus E, Tejasvi T, Chandran V, Pellett F, Pollock R, Bowcock AM, Krueger GG, Weichenthal M, Voorhees JJ, Rahman P, Gregersen PK, Franke A, Nair RP, Abecasis GR, Gladman DD, Elder JT, de Bakker PI, Raychaudhuri S. Okada Y, et al. Among authors: han b. Am J Hum Genet. 2014 Aug 7;95(2):162-72. doi: 10.1016/j.ajhg.2014.07.002. Epub 2014 Jul 31. Am J Hum Genet. 2014. PMID: 25087609 Free PMC article.
Variation at HLA-DRB1 is associated with resistance to enteric fever.
Dunstan SJ, Hue NT, Han B, Li Z, Tram TT, Sim KS, Parry CM, Chinh NT, Vinh H, Lan NP, Thieu NT, Vinh PV, Koirala S, Dongol S, Arjyal A, Karkey A, Shilpakar O, Dolecek C, Foo JN, Phuong le T, Lanh MN, Do T, Aung T, Hon DN, Teo YY, Hibberd ML, Anders KL, Okada Y, Raychaudhuri S, Simmons CP, Baker S, de Bakker PI, Basnyat B, Hien TT, Farrar JJ, Khor CC. Dunstan SJ, et al. Among authors: han b. Nat Genet. 2014 Dec;46(12):1333-6. doi: 10.1038/ng.3143. Epub 2014 Nov 10. Nat Genet. 2014. PMID: 25383971 Free PMC article.
Accurate and fast multiple-testing correction in eQTL studies.
Sul JH, Raj T, de Jong S, de Bakker PI, Raychaudhuri S, Ophoff RA, Stranger BE, Eskin E, Han B. Sul JH, et al. Among authors: han b. Am J Hum Genet. 2015 Jun 4;96(6):857-68. doi: 10.1016/j.ajhg.2015.04.012. Epub 2015 May 28. Am J Hum Genet. 2015. PMID: 26027500 Free PMC article.
9,298 results