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Page 1
Serial femtosecond crystallography of G protein-coupled receptors.
Liu W, Wacker D, Gati C, Han GW, James D, Wang D, Nelson G, Weierstall U, Katritch V, Barty A, Zatsepin NA, Li D, Messerschmidt M, Boutet S, Williams GJ, Koglin JE, Seibert MM, Wang C, Shah ST, Basu S, Fromme R, Kupitz C, Rendek KN, Grotjohann I, Fromme P, Kirian RA, Beyerlein KR, White TA, Chapman HN, Caffrey M, Spence JC, Stevens RC, Cherezov V. Liu W, et al. Among authors: han gw. Science. 2013 Dec 20;342(6165):1521-4. doi: 10.1126/science.1244142. Science. 2013. PMID: 24357322 Free PMC article.
Crystal structure of an alanine-glyoxylate aminotransferase from Anabaena sp. at 1.70 A resolution reveals a noncovalently linked PLP cofactor.
Han GW, Schwarzenbacher R, Page R, Jaroszewski L, Abdubek P, Ambing E, Biorac T, Canaves JM, Chiu HJ, Dai X, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hale J, Hampton E, Haugen J, Hornsby M, Klock HE, Koesema E, Kreusch A, Kuhn P, Lesley SA, Levin I, McMullan D, McPhillips TM, Miller MD, Morse A, Moy K, Nigoghossian E, Ouyang J, Paulsen J, Quijano K, Reyes R, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, von Delft F, Wang X, West B, White A, Wolf G, Xu Q, Zagnitko O, Hodgson KO, Wooley J, Wilson IA. Han GW, et al. Proteins. 2005 Mar 1;58(4):971-5. doi: 10.1002/prot.20360. Proteins. 2005. PMID: 15657930 No abstract available.
Crystal structure of an indigoidine synthase A (IndA)-like protein (TM1464) from Thermotoga maritima at 1.90 A resolution reveals a new fold.
Levin I, Miller MD, Schwarzenbacher R, McMullan D, Abdubek P, Ambing E, Biorac T, Cambell J, Canaves JM, Chiu HJ, Deacon AM, DiDonato M, Elsliger MA, Godzik A, Grittini C, Grzechnik SK, Hale J, Hampton E, Han GW, Haugen J, Hornsby M, Jaroszewski L, Karlak C, Klock HE, Koesema E, Kreusch A, Kuhn P, Lesley SA, Morse A, Moy K, Nigoghossian E, Ouyang J, Page R, Quijano K, Reyes R, Robb A, Sims E, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, Vincent J, Wang X, West B, Wolf G, Xu Q, Zagnitko O, Hodgson KO, Wooley J, Wilson IA. Levin I, et al. Among authors: han gw. Proteins. 2005 Jun 1;59(4):864-8. doi: 10.1002/prot.20420. Proteins. 2005. PMID: 15822122 No abstract available.
Structure of an agonist-bound human A2A adenosine receptor.
Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC. Xu F, et al. Among authors: han gw. Science. 2011 Apr 15;332(6027):322-7. doi: 10.1126/science.1202793. Epub 2011 Mar 10. Science. 2011. PMID: 21393508 Free PMC article.
Structural characterization of three novel hydroxamate-based zinc chelating inhibitors of the Clostridium botulinum serotype A neurotoxin light chain metalloprotease reveals a compact binding site resulting from 60/70 loop flexibility.
Thompson AA, Jiao GS, Kim S, Thai A, Cregar-Hernandez L, Margosiak SA, Johnson AT, Han GW, O'Malley S, Stevens RC. Thompson AA, et al. Among authors: han gw. Biochemistry. 2011 May 17;50(19):4019-28. doi: 10.1021/bi2001483. Epub 2011 Apr 21. Biochemistry. 2011. PMID: 21434688 Free PMC article.
Structure of the human histamine H1 receptor complex with doxepin.
Shimamura T, Shiroishi M, Weyand S, Tsujimoto H, Winter G, Katritch V, Abagyan R, Cherezov V, Liu W, Han GW, Kobayashi T, Stevens RC, Iwata S. Shimamura T, et al. Among authors: han gw. Nature. 2011 Jun 22;475(7354):65-70. doi: 10.1038/nature10236. Nature. 2011. PMID: 21697825 Free PMC article.
Crystal structure of a lipid G protein-coupled receptor.
Hanson MA, Roth CB, Jo E, Griffith MT, Scott FL, Reinhart G, Desale H, Clemons B, Cahalan SM, Schuerer SC, Sanna MG, Han GW, Kuhn P, Rosen H, Stevens RC. Hanson MA, et al. Among authors: han gw. Science. 2012 Feb 17;335(6070):851-5. doi: 10.1126/science.1215904. Science. 2012. PMID: 22344443 Free PMC article.
189 results