Harris LA - Search Results

1

Quantifying Drug Combination Synergy along Potency and Efficacy Axes.

Meyer CT, Wooten DJ, Paudel BB, Bauer J, Hardeman KN, Westover D, Lovly CM, Harris LA, Tyson DR, Quaranta V. Meyer CT, et al. Among authors: harris la. Cell Syst. 2019 Feb 27;8(2):97-108.e16. doi: 10.1016/j.cels.2019.01.003. Epub 2019 Feb 20. Cell Syst. 2019. PMID: 30797775 Free PMC article.

2

An unbiased metric of antiproliferative drug effect in vitro.

Harris LA, Frick PL, Garbett SP, Hardeman KN, Paudel BB, Lopez CF, Quaranta V, Tyson DR. Harris LA, et al. Nat Methods. 2016 Jun;13(6):497-500. doi: 10.1038/nmeth.3852. Epub 2016 May 2. Nat Methods. 2016. PMID: 27135974 Free PMC article.

3

A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase.

Jones ZW, Leander R, Quaranta V, Harris LA, Tyson DR. Jones ZW, et al. Among authors: harris la. PLoS One. 2018 Feb 12;13(2):e0192087. doi: 10.1371/journal.pone.0192087. eCollection 2018. PLoS One. 2018. PMID: 29432467 Free PMC article.

4

A Nonquiescent "Idling" Population State in Drug-Treated, BRAF-Mutated Melanoma.

Paudel BB, Harris LA, Hardeman KN, Abugable AA, Hayford CE, Tyson DR, Quaranta V. Paudel BB, et al. Among authors: harris la. Biophys J. 2018 Mar 27;114(6):1499-1511. doi: 10.1016/j.bpj.2018.01.016. Biophys J. 2018. PMID: 29590606 Free PMC article.

5

Thunor: visualization and analysis of high-throughput dose-response datasets.

Lubbock ALR, Harris LA, Quaranta V, Tyson DR, Lopez CF. Lubbock ALR, et al. Among authors: harris la. Nucleic Acids Res. 2021 Jul 2;49(W1):W633-W640. doi: 10.1093/nar/gkab424. Nucleic Acids Res. 2021. PMID: 34038546 Free PMC article.

6

An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability.

Hayford CE, Tyson DR, Robbins CJ 3rd, Frick PL, Quaranta V, Harris LA. Hayford CE, et al. Among authors: harris la. PLoS Biol. 2021 Jun 1;19(6):e3000797. doi: 10.1371/journal.pbio.3000797. eCollection 2021 Jun. PLoS Biol. 2021. PMID: 34061819 Free PMC article.

7

Real-time luminescence enables continuous drug-response analysis in adherent and suspension cell lines.

Wandishin CM, Robbins CJ, Tyson DR, Harris LA, Quaranta V. Wandishin CM, et al. Among authors: harris la. Cancer Biol Ther. 2022 Dec 31;23(1):358-368. doi: 10.1080/15384047.2022.2065182. Cancer Biol Ther. 2022. PMID: 35443861 Free PMC article.

8

Involvement of Epithelial-Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity.

Groves SM, Panchy N, Tyson DR, Harris LA, Quaranta V, Hong T. Groves SM, et al. Among authors: harris la. Cancers (Basel). 2023 Feb 25;15(5):1477. doi: 10.3390/cancers15051477. Cancers (Basel). 2023. PMID: 36900269 Free PMC article.

9

Unified tumor growth mechanisms from multimodel inference and dataset integration.

Beik SP, Harris LA, Kochen MA, Sage J, Quaranta V, Lopez CF. Beik SP, et al. Among authors: harris la. PLoS Comput Biol. 2023 Jul 5;19(7):e1011215. doi: 10.1371/journal.pcbi.1011215. eCollection 2023 Jul. PLoS Comput Biol. 2023. PMID: 37406008 Free PMC article.

10

Modeling heterogeneous tumor growth dynamics and cell-cell interactions at single-cell and cell-population resolution.

Harris LA, Beik S, Ozawa PMM, Jimenez L, Weaver AM. Harris LA, et al. Curr Opin Syst Biol. 2019 Oct;17:24-34. doi: 10.1016/j.coisb.2019.09.005. Epub 2019 Sep 16. Curr Opin Syst Biol. 2019. PMID: 32642602 Free PMC article.

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