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Dipeptide repeat proteins are present in the p62 positive inclusions in patients with frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72.
Mann DM, Rollinson S, Robinson A, Bennion Callister J, Thompson JC, Snowden JS, Gendron T, Petrucelli L, Masuda-Suzukake M, Hasegawa M, Davidson Y, Pickering-Brown S. Mann DM, et al. Among authors: hasegawa m. Acta Neuropathol Commun. 2013 Oct 14;1:68. doi: 10.1186/2051-5960-1-68. Acta Neuropathol Commun. 2013. PMID: 24252525 Free PMC article.
TDP-43 in ubiquitinated inclusions in the inferior olives in frontotemporal lobar degeneration and in other neurodegenerative diseases: a degenerative process distinct from normal ageing.
Davidson Y, Amin H, Kelley T, Shi J, Tian J, Kumaran R, Lashley T, Lees AJ, DuPlessis D, Neary D, Snowden J, Akiyama H, Arai T, Hasegawa M, Bandopadhyay R, Sikkink S, Pickering-Brown S, Mann DM. Davidson Y, et al. Among authors: hasegawa m. Acta Neuropathol. 2009 Sep;118(3):359-69. doi: 10.1007/s00401-009-0526-z. Epub 2009 Mar 28. Acta Neuropathol. 2009. PMID: 19330339
Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration.
Foulds PG, Davidson Y, Mishra M, Hobson DJ, Humphreys KM, Taylor M, Johnson N, Weintraub S, Akiyama H, Arai T, Hasegawa M, Bigio EH, Benson FE, Allsop D, Mann DM. Foulds PG, et al. Among authors: hasegawa m. Acta Neuropathol. 2009 Nov;118(5):647-58. doi: 10.1007/s00401-009-0594-0. Epub 2009 Oct 13. Acta Neuropathol. 2009. PMID: 19823856 Free PMC article.
Epitope mapping of antibodies against TDP-43 and detection of protease-resistant fragments of pathological TDP-43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Tsuji H, Nonaka T, Yamashita M, Masuda-Suzukake M, Kametani F, Akiyama H, Mann DM, Tamaoka A, Hasegawa M. Tsuji H, et al. Among authors: hasegawa m. Biochem Biophys Res Commun. 2012 Jan 6;417(1):116-21. doi: 10.1016/j.bbrc.2011.11.066. Epub 2011 Nov 22. Biochem Biophys Res Commun. 2012. PMID: 22133678
Molecular analysis and biochemical classification of TDP-43 proteinopathy.
Tsuji H, Arai T, Kametani F, Nonaka T, Yamashita M, Suzukake M, Hosokawa M, Yoshida M, Hatsuta H, Takao M, Saito Y, Murayama S, Akiyama H, Hasegawa M, Mann DM, Tamaoka A. Tsuji H, et al. Among authors: hasegawa m. Brain. 2012 Nov;135(Pt 11):3380-91. doi: 10.1093/brain/aws230. Epub 2012 Oct 3. Brain. 2012. PMID: 23035040
Prion-like spreading of pathological α-synuclein in brain.
Masuda-Suzukake M, Nonaka T, Hosokawa M, Oikawa T, Arai T, Akiyama H, Mann DM, Hasegawa M. Masuda-Suzukake M, et al. Among authors: hasegawa m. Brain. 2013 Apr;136(Pt 4):1128-38. doi: 10.1093/brain/awt037. Epub 2013 Mar 6. Brain. 2013. PMID: 23466394 Free PMC article.
4,124 results