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Page 1
Showing results for heavily nd
Search for Heavilin ND instead (2 results)
Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure.
Hughes TP, Mauro MJ, Cortes JE, Minami H, Rea D, DeAngelo DJ, Breccia M, Goh YT, Talpaz M, Hochhaus A, le Coutre P, Ottmann O, Heinrich MC, Steegmann JL, Deininger MWN, Janssen JJWM, Mahon FX, Minami Y, Yeung D, Ross DM, Tallman MS, Park JH, Druker BJ, Hynds D, Duan Y, Meille C, Hourcade-Potelleret F, Vanasse KG, Lang F, Kim DW. Hughes TP, et al. N Engl J Med. 2019 Dec 12;381(24):2315-2326. doi: 10.1056/NEJMoa1902328. N Engl J Med. 2019. PMID: 31826340 Free PMC article. Clinical Trial.
Asciminib was administered once or twice daily (at doses of 10 to 200 mg). The median follow-up was 14 months. RESULTS: Patients were heavily pretreated; 70% (105 of 150 patients) had received at least three TKIs. ...Common adverse events included fatigue, headache, arthra …
Asciminib was administered once or twice daily (at doses of 10 to 200 mg). The median follow-up was 14 months. RESULTS: Patients were hea …
Trends in Biological Ammonia Production.
Adeniyi A, Bello I, Mukaila T, Sarker NC, Hammed A. Adeniyi A, et al. BioTech (Basel). 2023 May 19;12(2):41. doi: 10.3390/biotech12020041. BioTech (Basel). 2023. PMID: 37218758 Free PMC article. Review.
Food production heavily depends on ammonia-containing fertilizers to improve crop yield and profitability. ...
Food production heavily depends on ammonia-containing fertilizers to improve crop yield and profitability. ...
Effector Identification in Plant Pathogens.
Lovelace AH, Dorhmi S, Hulin MT, Li Y, Mansfield JW, Ma W. Lovelace AH, et al. Phytopathology. 2023 Apr;113(4):637-650. doi: 10.1094/PHYTO-09-22-0337-KD. Epub 2023 Apr 26. Phytopathology. 2023. PMID: 37126080 Free article. Review.
A foundation of this research is robust identification of the effector repertoire from a given pathogen, which depends heavily on bioinformatic prediction. In this review, we summarize methodologies that have been used for effector mining in various microbial pathogens whi …
A foundation of this research is robust identification of the effector repertoire from a given pathogen, which depends heavily on bio …
Targeted Nanobody-Based Molecular Tracers for Nuclear Imaging and Image-Guided Surgery.
Debie P, Devoogdt N, Hernot S. Debie P, et al. Antibodies (Basel). 2019 Jan 11;8(1):12. doi: 10.3390/antib8010012. Antibodies (Basel). 2019. PMID: 31544818 Free PMC article. Review.
Nanobody-based tracers using either nuclear or fluorescent labels have been heavily investigated preclinically and are currently making their way into the clinic. ...
Nanobody-based tracers using either nuclear or fluorescent labels have been heavily investigated preclinically and are currently maki …
Metabolism of Glycosphingolipids and Their Role in the Pathophysiology of Lysosomal Storage Disorders.
Ryckman AE, Brockhausen I, Walia JS. Ryckman AE, et al. Int J Mol Sci. 2020 Sep 19;21(18):6881. doi: 10.3390/ijms21186881. Int J Mol Sci. 2020. PMID: 32961778 Free PMC article. Review.
Of the hundreds of unique GSL structures, anionic gangliosides are the most heavily implicated in the pathogenesis of lysosomal storage diseases (LSDs) such as Tay-Sachs and Sandhoff disease. ...
Of the hundreds of unique GSL structures, anionic gangliosides are the most heavily implicated in the pathogenesis of lysosomal stora …
Current Immunotherapy Treatments of Primary Breast Cancer Subtypes.
Brown SR, Vomhof-DeKrey EE. Brown SR, et al. Biomedicines. 2024 Apr 18;12(4):895. doi: 10.3390/biomedicines12040895. Biomedicines. 2024. PMID: 38672249 Free PMC article. Review.
Nevertheless, this malignancy remains the most diagnosed cancer among women and relies heavily on a neoadjuvant treatment regimen of chemotherapy and targeted therapy. ...
Nevertheless, this malignancy remains the most diagnosed cancer among women and relies heavily on a neoadjuvant treatment regimen of …
The effects of microRNA on the absorption, distribution, metabolism and excretion of drugs.
He Y, Chevillet JR, Liu G, Kim TK, Wang K. He Y, et al. Br J Pharmacol. 2015 Jun;172(11):2733-47. doi: 10.1111/bph.12968. Epub 2014 Dec 1. Br J Pharmacol. 2015. PMID: 25296724 Free PMC article. Review.
Our ability to identify, interpret and utilize these factors is the subject of much clinical investigation and therapeutic development. However, drug ADME and efficacy are also heavily influenced by epigenetic factors such as DNA/histone methylation and non-coding RNAs [es …
Our ability to identify, interpret and utilize these factors is the subject of much clinical investigation and therapeutic development. Howe …
Multiple myeloma mesenchymal stem cells: characterization, origin, and tumor-promoting effects.
Reagan MR, Ghobrial IM. Reagan MR, et al. Clin Cancer Res. 2012 Jan 15;18(2):342-9. doi: 10.1158/1078-0432.CCR-11-2212. Epub 2011 Nov 7. Clin Cancer Res. 2012. PMID: 22065077 Free PMC article. Review.
Hematologic malignancies rely heavily on support from host cells through a number of well-documented mechanisms. ...However, before the scientific community can capitalize on the distinctions between MM-MSCs and ND-MSCs, a number of confusions must be clarified, as …
Hematologic malignancies rely heavily on support from host cells through a number of well-documented mechanisms. ...However, before t …
Spine surgery in Nepal: the 2015 earthquake.
Sutterlin CE 3rd. Sutterlin CE 3rd. J Spine Surg. 2015 Dec;1(1):28-34. doi: 10.3978/j.issn.2414-469X.2015.10.04. J Spine Surg. 2015. PMID: 27683676 Free PMC article. Review.
The violent tremors were felt as far away as New Delhi, India 1,000 km from the epicenter, but the worst of its destructive force was experienced in the heavily populated Kathmandu valley and in the remote mountainous villages of the Himalaya. ...Spinal Health Internationa …
The violent tremors were felt as far away as New Delhi, India 1,000 km from the epicenter, but the worst of its destructive force was experi …
From Widely Accepted Concepts in Coordination Chemistry to Inverted Ligand Fields.
Hoffmann R, Alvarez S, Mealli C, Falceto A, Cahill TJ 3rd, Zeng T, Manca G. Hoffmann R, et al. Chem Rev. 2016 Jul 27;116(14):8173-92. doi: 10.1021/acs.chemrev.6b00251. Epub 2016 Jul 11. Chem Rev. 2016. PMID: 27398715 Review.
We begin with a brief historical review of the development of our understanding of the normal ordering of nd orbitals of a transition metal interacting with ligands, the most common cases being three below two in an octahedral environment, two below three in tetrahedral co …
We begin with a brief historical review of the development of our understanding of the normal ordering of nd orbitals of a transition …
159 results