Heggelund JE - Search Results

1

The human homolog of Escherichia coli endonuclease V is a nucleolar protein with affinity for branched DNA structures.

Fladeby C, Vik ES, Laerdahl JK, Gran Neurauter C, Heggelund JE, Thorgaard E, Strøm-Andersen P, Bjørås M, Dalhus B, Alseth I. Fladeby C, et al. Among authors: heggelund je. PLoS One. 2012;7(11):e47466. doi: 10.1371/journal.pone.0047466. Epub 2012 Nov 5. PLoS One. 2012. PMID: 23139746 Free PMC article.

2

Specificity of Escherichia coli Heat-Labile Enterotoxin Investigated by Single-Site Mutagenesis and Crystallography.

Heggelund JE, Heim JB, Bajc G, Hodnik V, Anderluh G, Krengel U. Heggelund JE, et al. Int J Mol Sci. 2019 Feb 6;20(3):703. doi: 10.3390/ijms20030703. Int J Mol Sci. 2019. PMID: 30736336 Free PMC article.

3

Both El Tor and classical cholera toxin bind blood group determinants.

Heggelund JE, Haugen E, Lygren B, Mackenzie A, Holmner Å, Vasile F, Reina JJ, Bernardi A, Krengel U. Heggelund JE, et al. Biochem Biophys Res Commun. 2012 Feb 24;418(4):731-5. doi: 10.1016/j.bbrc.2012.01.089. Epub 2012 Jan 28. Biochem Biophys Res Commun. 2012. PMID: 22305717

4

High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence.

Heggelund JE, Burschowsky D, Bjørnestad VA, Hodnik V, Anderluh G, Krengel U. Heggelund JE, et al. PLoS Pathog. 2016 Apr 15;12(4):e1005567. doi: 10.1371/journal.ppat.1005567. eCollection 2016 Apr. PLoS Pathog. 2016. PMID: 27082955 Free PMC article.

5

¹H, ¹³C, ¹⁵N backbone assignment of the human heat-labile enterotoxin B-pentamer and chemical shift mapping of neolactotetraose binding.

Hatlem D, Heggelund JE, Burschowsky D, Krengel U, Kristiansen PE. Hatlem D, et al. Among authors: heggelund je. Biomol NMR Assign. 2017 Apr;11(1):99-104. doi: 10.1007/s12104-017-9728-9. Epub 2017 Feb 27. Biomol NMR Assign. 2017. PMID: 28243889

6

Comprehensive analysis of blood group antigen binding to classical and El Tor cholera toxin B-pentamers by NMR.

Vasile F, Reina JJ, Potenza D, Heggelund JE, Mackenzie A, Krengel U, Bernardi A. Vasile F, et al. Among authors: heggelund je. Glycobiology. 2014 Aug;24(8):766-78. doi: 10.1093/glycob/cwu040. Epub 2014 May 14. Glycobiology. 2014. PMID: 24829308 Free article.

7

Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics.

Heggelund JE, Mackenzie A, Martinsen T, Heim JB, Cheshev P, Bernardi A, Krengel U. Heggelund JE, et al. Sci Rep. 2017 May 24;7(1):2326. doi: 10.1038/s41598-017-02179-0. Sci Rep. 2017. PMID: 28539625 Free PMC article.

8

Histo-blood group antigens as mediators of infections.

Heggelund JE, Varrot A, Imberty A, Krengel U. Heggelund JE, et al. Curr Opin Struct Biol. 2017 Jun;44:190-200. doi: 10.1016/j.sbi.2017.04.001. Epub 2017 May 23. Curr Opin Struct Biol. 2017. PMID: 28544984 Review.

9

Crystal structure of an L chain optimised 14F7 anti-ganglioside Fv suggests a unique tumour-specificity through an unusual H-chain CDR3 architecture.

Bjerregaard-Andersen K, Johannesen H, Abdel-Rahman N, Heggelund JE, Hoås HM, Abraha F, Bousquet PA, Høydahl LS, Burschowsky D, Rojas G, Oscarson S, Løset GÅ, Krengel U. Bjerregaard-Andersen K, et al. Among authors: heggelund je. Sci Rep. 2018 Jul 18;8(1):10836. doi: 10.1038/s41598-018-28918-5. Sci Rep. 2018. PMID: 30022069 Free PMC article.

10

Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site.

Heim JB, Hodnik V, Heggelund JE, Anderluh G, Krengel U. Heim JB, et al. Among authors: heggelund je. Sci Rep. 2019 Aug 22;9(1):12243. doi: 10.1038/s41598-019-48579-2. Sci Rep. 2019. PMID: 31439922 Free PMC article.

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