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Rapid in vivo measurement of β-amyloid reveals biphasic clearance kinetics in an Alzheimer's mouse model.
J Exp Med. 2016 May 2;213(5):677-85. doi: 10.1084/jem.20151428. Epub 2016 Apr 11.
J Exp Med. 2016.
PMID: 27069115
Free PMC article.
AMPA-ergic regulation of amyloid-β levels in an Alzheimer's disease mouse model.
Hettinger JC, Lee H, Bu G, Holtzman DM, Cirrito JR.
Hettinger JC, et al.
Mol Neurodegener. 2018 May 15;13(1):22. doi: 10.1186/s13024-018-0256-6.
Mol Neurodegener. 2018.
PMID: 29764453
Free PMC article.
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Pimavanserin, a 5HT2A receptor inverse agonist, rapidly suppresses Aβ production and related pathology in a mouse model of Alzheimer's disease.
Yuede CM, Wallace CE, Davis TA, Gardiner WD, Hettinger JC, Edwards HM, Hendrix RD, Doherty BM, Yuede KM, Burstein ES, Cirrito JR.
Yuede CM, et al. Among authors: hettinger jc.
J Neurochem. 2021 Mar;156(5):658-673. doi: 10.1111/jnc.15260. Epub 2021 Jan 10.
J Neurochem. 2021.
PMID: 33278025
Free PMC article.
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Reply to comment on "An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice".
Sheline YI, West T, Yarasheski K, Jasielec MS, Hettinger JC, Tripoli DL, Xiong C, Frederiksen C, Grzelak MV, Bateman RJ, Morris JC, Lee JM, Cirrito JR.
Sheline YI, et al. Among authors: hettinger jc.
Sci Transl Med. 2014 Dec 24;6(268):268lr4. doi: 10.1126/scitranslmed.3010609.
Sci Transl Med. 2014.
PMID: 25540323
Free PMC article.
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Bad Ac-etylated Tau.
Hettinger JC, Cirrito JR.
Hettinger JC, et al.
Neuron. 2016 Apr 20;90(2):205-6. doi: 10.1016/j.neuron.2016.04.008.
Neuron. 2016.
PMID: 27100190
Free article.
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Interactions between stress and physical activity on Alzheimer's disease pathology.
Yuede CM, Timson BF, Hettinger JC, Yuede KM, Edwards HM, Lawson JE, Zimmerman SD, Cirrito JR.
Yuede CM, et al. Among authors: hettinger jc.
Neurobiol Stress. 2018 Feb 22;8:158-171. doi: 10.1016/j.ynstr.2018.02.004. eCollection 2018 Feb.
Neurobiol Stress. 2018.
PMID: 29888311
Free PMC article.
Review.
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p66(shc)'s role as an essential mitophagic molecule in controlling neuronal redox and energetic tone.
Kleman AM, Brown JE, Zeiger SL, Hettinger JC, Brooks JD, Holt B, Morrow JD, Musiek ES, Milne GL, McLaughlin B.
Kleman AM, et al. Among authors: hettinger jc.
Autophagy. 2010 Oct;6(7):948-9. doi: 10.1523/j.neurosci.6366-09.2010. Epub 2010 Oct 14.
Autophagy. 2010.
PMID: 20724835
Free PMC article.
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Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning.
Brown JE, Zeiger SL, Hettinger JC, Brooks JD, Holt B, Morrow JD, Musiek ES, Milne G, McLaughlin B.
Brown JE, et al. Among authors: hettinger jc.
J Neurosci. 2010 Apr 14;30(15):5242-52. doi: 10.1523/JNEUROSCI.6366-09.2010.
J Neurosci. 2010.
PMID: 20392947
Free PMC article.
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