Higham J - Search Results

1

Genotype effects contribute to variation in longitudinal methylome patterns in older people.

Zhang Q, Marioni RE, Robinson MR, Higham J, Sproul D, Wray NR, Deary IJ, McRae AF, Visscher PM. Zhang Q, et al. Among authors: higham j. Genome Med. 2018 Oct 22;10(1):75. doi: 10.1186/s13073-018-0585-7. Genome Med. 2018. PMID: 30348214 Free PMC article.

2

Local CpG density affects the trajectory and variance of age-associated DNA methylation changes.

Higham J, Kerr L, Zhang Q, Walker RM, Harris SE, Howard DM, Hawkins EL, Sandu AL, Steele JD, Waiter GD, Murray AD, Evans KL, McIntosh AM, Visscher PM, Deary IJ, Cox SR, Sproul D. Higham J, et al. Genome Biol. 2022 Oct 17;23(1):216. doi: 10.1186/s13059-022-02787-8. Genome Biol. 2022. PMID: 36253871 Free PMC article.

3

Age-related clonal haemopoiesis is associated with increased epigenetic age.

Robertson NA, Hillary RF, McCartney DL, Terradas-Terradas M, Higham J, Sproul D, Deary IJ, Kirschner K, Marioni RE, Chandra T. Robertson NA, et al. Among authors: higham j. Curr Biol. 2019 Aug 19;29(16):R786-R787. doi: 10.1016/j.cub.2019.07.011. Curr Biol. 2019. PMID: 31430471 Free article.

4

An epigenetic predictor of death captures multi-modal measures of brain health.

Hillary RF, Stevenson AJ, Cox SR, McCartney DL, Harris SE, Seeboth A, Higham J, Sproul D, Taylor AM, Redmond P, Corley J, Pattie A, Hernández MDCV, Muñoz-Maniega S, Bastin ME, Wardlaw JM, Horvath S, Ritchie CW, Spires-Jones TL, McIntosh AM, Evans KL, Deary IJ, Marioni RE. Hillary RF, et al. Among authors: higham j. Mol Psychiatry. 2021 Aug;26(8):3806-3816. doi: 10.1038/s41380-019-0616-9. Epub 2019 Dec 3. Mol Psychiatry. 2021. PMID: 31796892 Free PMC article.

5

Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation.

Patani H, Rushton MD, Higham J, Teijeiro SA, Oxley D, Cutillas P, Sproul D, Ficz G. Patani H, et al. Among authors: higham j. Nat Commun. 2020 Jul 22;11(1):3671. doi: 10.1038/s41467-020-17269-3. Nat Commun. 2020. PMID: 32699299 Free PMC article.

6

De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands.

Masalmeh RHA, Taglini F, Rubio-Ramon C, Musialik KI, Higham J, Davidson-Smith H, Kafetzopoulos I, Pawlicka KP, Finan HM, Clark R, Wills J, Finch AJ, Murphy L, Sproul D. Masalmeh RHA, et al. Among authors: higham j. Nat Commun. 2021 Jan 29;12(1):694. doi: 10.1038/s41467-020-20716-w. Nat Commun. 2021. PMID: 33514701 Free PMC article.

7

Gingipain-dependent degradation of mammalian target of rapamycin pathway proteins by the periodontal pathogen Porphyromonas gingivalis during invasion.

Stafford P, Higham J, Pinnock A, Murdoch C, Douglas CW, Stafford GP, Lambert DW. Stafford P, et al. Among authors: higham j. Mol Oral Microbiol. 2013 Oct;28(5):366-78. doi: 10.1111/omi.12030. Epub 2013 May 29. Mol Oral Microbiol. 2013. PMID: 23714361 Free PMC article.

8

Mediterranean diet and risk of Sjögren's syndrome.

Machowicz A, Hall I, de Pablo P, Rauz S, Richards A, Higham J, Poveda-Gallego A, Imamura F, Bowman SJ, Barone F, Fisher BA. Machowicz A, et al. Among authors: higham j. Clin Exp Rheumatol. 2020 Jul-Aug;38 Suppl 126(4):216-221. Epub 2020 Oct 23. Clin Exp Rheumatol. 2020. PMID: 33095150 Free article.

9

Entropy of Proteins Using Multiscale Cell Correlation.

Chakravorty A, Higham J, Henchman RH. Chakravorty A, et al. Among authors: higham j. J Chem Inf Model. 2020 Nov 23;60(11):5540-5551. doi: 10.1021/acs.jcim.0c00611. Epub 2020 Sep 29. J Chem Inf Model. 2020. PMID: 32955869

10

Comparison of Free-Energy Methods to Calculate the Barriers for the Nucleophilic Substitution of Alkyl Halides by Hydroxide.

Ali HS, Higham J, de Visser SP, Henchman RH. Ali HS, et al. Among authors: higham j. J Phys Chem B. 2020 Aug 6;124(31):6835-6842. doi: 10.1021/acs.jpcb.0c02264. Epub 2020 Jul 27. J Phys Chem B. 2020. PMID: 32648760

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