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Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia.
Sejersted Y, Hildrestrand GA, Kunke D, Rolseth V, Krokeide SZ, Neurauter CG, Suganthan R, Atneosen-Åsegg M, Fleming AM, Saugstad OD, Burrows CJ, Luna L, Bjørås M. Sejersted Y, et al. Among authors: hildrestrand ga. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18802-7. doi: 10.1073/pnas.1106880108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065741 Free PMC article.
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.
Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A, Folkersen L, Ueland T, Berge RK, Hansson GK, Biessen EA, Halvorsen B, Bjørås M, Aukrust P. Skarpengland T, et al. Sci Rep. 2016 Jun 22;6:28337. doi: 10.1038/srep28337. Sci Rep. 2016. PMID: 27328939 Free PMC article.
Loss of Neil3, the major DNA glycosylase activity for removal of hydantoins in single stranded DNA, reduces cellular proliferation and sensitizes cells to genotoxic stress.
Rolseth V, Krokeide SZ, Kunke D, Neurauter CG, Suganthan R, Sejersted Y, Hildrestrand GA, Bjørås M, Luna L. Rolseth V, et al. Among authors: hildrestrand ga. Biochim Biophys Acta. 2013 May;1833(5):1157-64. doi: 10.1016/j.bbamcr.2012.12.024. Epub 2013 Jan 7. Biochim Biophys Acta. 2013. PMID: 23305905 Free article.
NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture.
Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JDS, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, Brorson SH, Zhang L, Gullestad L, Louch WE, Iversen PO, Østlie I, Klungland A, Christensen G, Sjaastad I, Sætrom P, Yndestad A, Aukrust P, Bjørås M, Finsen AV. Olsen MB, et al. Among authors: hildrestrand ga. Cell Rep. 2017 Jan 3;18(1):82-92. doi: 10.1016/j.celrep.2016.12.009. Cell Rep. 2017. PMID: 28052262 Free article.
No cancer predisposition or increased spontaneous mutation frequencies in NEIL DNA glycosylases-deficient mice.
Rolseth V, Luna L, Olsen AK, Suganthan R, Scheffler K, Neurauter CG, Esbensen Y, Kuśnierczyk A, Hildrestrand GA, Graupner A, Andersen JM, Slupphaug G, Klungland A, Nilsen H, Bjørås M. Rolseth V, et al. Among authors: hildrestrand ga. Sci Rep. 2017 Jun 29;7(1):4384. doi: 10.1038/s41598-017-04472-4. Sci Rep. 2017. PMID: 28663564 Free PMC article.
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