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Hyperinsulinemia enhances interleukin-17-induced inflammation to promote prostate cancer development in obese mice through inhibiting glycogen synthase kinase 3-mediated phosphorylation and degradation of interleukin-17 receptor.
Liu S, Zhang Q, Chen C, Ge D, Qu Y, Chen R, Fan YM, Li N, Tang WW, Zhang W, Zhang K, Wang AR, Rowan BG, Hill SM, Sartor O, Abdel-Mageed AB, Myers L, Lin Q, You Z. Liu S, et al. Among authors: hill sm. Oncotarget. 2016 Mar 22;7(12):13651-66. doi: 10.18632/oncotarget.7296. Oncotarget. 2016. PMID: 26871944 Free PMC article.
Gαo potentiates estrogen receptor α activity via the ERK signaling pathway.
Bratton MR, Antoon JW, Duong BN, Frigo DE, Tilghman S, Collins-Burow BM, Elliott S, Tang Y, Melnik LI, Lai L, Alam J, Beckman BS, Hill SM, Rowan BG, McLachlan JA, Burow ME. Bratton MR, et al. Among authors: hill sm. J Endocrinol. 2012 Jul;214(1):45-54. doi: 10.1530/JOE-12-0097. Epub 2012 May 4. J Endocrinol. 2012. PMID: 22562654 Free PMC article.
Stable inhibition of specific estrogen receptor α (ERα) phosphorylation confers increased growth, migration/invasion, and disruption of estradiol signaling in MCF-7 breast cancer cells.
Huderson BP, Duplessis TT, Williams CC, Seger HC, Marsden CG, Pouey KJ, Hill SM, Rowan BG. Huderson BP, et al. Among authors: hill sm. Endocrinology. 2012 Sep;153(9):4144-59. doi: 10.1210/en.2011-2001. Epub 2012 Jun 25. Endocrinology. 2012. PMID: 22733972 Free PMC article.
198 results