Hills R - Search Results

1

EZH2 mutations are frequent and represent an early event in follicular lymphoma.

Bödör C, Grossmann V, Popov N, Okosun J, O'Riain C, Tan K, Marzec J, Araf S, Wang J, Lee AM, Clear A, Montoto S, Matthews J, Iqbal S, Rajnai H, Rosenwald A, Ott G, Campo E, Rimsza LM, Smeland EB, Chan WC, Braziel RM, Staudt LM, Wright G, Lister TA, Elemento O, Hills R, Gribben JG, Chelala C, Matolcsy A, Kohlmann A, Haferlach T, Gascoyne RD, Fitzgibbon J. Bödör C, et al. Among authors: hills r. Blood. 2013 Oct 31;122(18):3165-8. doi: 10.1182/blood-2013-04-496893. Epub 2013 Sep 19. Blood. 2013. PMID: 24052547 Free PMC article.

2

Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia.

Gale RE, Hills R, Pizzey AR, Kottaridis PD, Swirsky D, Gilkes AF, Nugent E, Mills KI, Wheatley K, Solomon E, Burnett AK, Linch DC, Grimwade D; NCRI Adult Leukaemia Working Party. Gale RE, et al. Among authors: hills r. Blood. 2005 Dec 1;106(12):3768-76. doi: 10.1182/blood-2005-04-1746. Epub 2005 Aug 16. Blood. 2005. PMID: 16105978 Free article.

3

FLT3 tyrosine kinase domain mutations are biologically distinct from and have a significantly more favorable prognosis than FLT3 internal tandem duplications in patients with acute myeloid leukemia.

Mead AJ, Linch DC, Hills RK, Wheatley K, Burnett AK, Gale RE. Mead AJ, et al. Blood. 2007 Aug 15;110(4):1262-70. doi: 10.1182/blood-2006-04-015826. Epub 2007 Apr 24. Blood. 2007. PMID: 17456725 Free article.

4

Mutation of the Wilms' tumor 1 gene is a poor prognostic factor associated with chemotherapy resistance in normal karyotype acute myeloid leukemia: the United Kingdom Medical Research Council Adult Leukaemia Working Party.

Virappane P, Gale R, Hills R, Kakkas I, Summers K, Stevens J, Allen C, Green C, Quentmeier H, Drexler H, Burnett A, Linch D, Bonnet D, Lister TA, Fitzgibbon J. Virappane P, et al. Among authors: hills r. J Clin Oncol. 2008 Nov 20;26(33):5429-35. doi: 10.1200/JCO.2008.16.0333. Epub 2008 Jun 30. J Clin Oncol. 2008. PMID: 18591546

5

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers.

Pepper C, Lin TT, Pratt G, Hewamana S, Brennan P, Hiller L, Hills R, Ward R, Starczynski J, Austen B, Hooper L, Stankovic T, Fegan C. Pepper C, et al. Among authors: hills r. Blood. 2008 Nov 1;112(9):3807-17. doi: 10.1182/blood-2008-05-157131. Epub 2008 Jul 3. Blood. 2008. PMID: 18599795 Free article.

6

The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukemia is dependent on FLT3/ITD status.

Green CL, Evans CM, Hills RK, Burnett AK, Linch DC, Gale RE. Green CL, et al. Blood. 2010 Oct 14;116(15):2779-82. doi: 10.1182/blood-2010-02-270926. Epub 2010 Jul 22. Blood. 2010. PMID: 20651067 Free article. Clinical Trial.

7

The prognostic significance of IDH2 mutations in AML depends on the location of the mutation.

Green CL, Evans CM, Zhao L, Hills RK, Burnett AK, Linch DC, Gale RE. Green CL, et al. Blood. 2011 Jul 14;118(2):409-12. doi: 10.1182/blood-2010-12-322479. Epub 2011 May 19. Blood. 2011. PMID: 21596855 Free article.

8

A functional variant in the core promoter of the CD95 cell death receptor gene predicts prognosis in acute promyelocytic leukemia.

Sunter NJ, Scott K, Hills R, Grimwade D, Taylor S, Worrillow LJ, Fordham SE, Forster VJ, Jackson G, Bomken S, Jones G, Allan JM. Sunter NJ, et al. Among authors: hills r. Blood. 2012 Jan 5;119(1):196-205. doi: 10.1182/blood-2011-04-349803. Epub 2011 Nov 14. Blood. 2012. PMID: 22084312 Free article. Clinical Trial.

9

GATA2 mutations in sporadic and familial acute myeloid leukaemia patients with CEBPA mutations.

Green CL, Tawana K, Hills RK, Bödör C, Fitzgibbon J, Inglott S, Ancliff P, Burnett AK, Linch DC, Gale RE. Green CL, et al. Br J Haematol. 2013 Jun;161(5):701-705. doi: 10.1111/bjh.12317. Epub 2013 Apr 5. Br J Haematol. 2013. PMID: 23560626 Free article.

10

Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling.

Hole PS, Zabkiewicz J, Munje C, Newton Z, Pearn L, White P, Marquez N, Hills RK, Burnett AK, Tonks A, Darley RL. Hole PS, et al. Blood. 2013 Nov 7;122(19):3322-30. doi: 10.1182/blood-2013-04-491944. Epub 2013 Oct 2. Blood. 2013. PMID: 24089327 Free article.

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