Hilton JB - Search Results

1

Cu^II(atsm) improves the neurological phenotype and survival of SOD1^G93A mice and selectively increases enzymatically active SOD1 in the spinal cord.

Hilton JB, Mercer SW, Lim NK, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ. Hilton JB, et al. Sci Rep. 2017 Feb 13;7:42292. doi: 10.1038/srep42292. Sci Rep. 2017. PMID: 28205575 Free PMC article.

2

Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.

Lim NK, Hung LW, Pang TY, Mclean CA, Liddell JR, Hilton JB, Li QX, White AR, Hannan AJ, Crouch PJ. Lim NK, et al. Among authors: hilton jb. Hum Mol Genet. 2014 Aug 1;23(15):4051-63. doi: 10.1093/hmg/ddu119. Epub 2014 Mar 14. Hum Mol Genet. 2014. PMID: 24634145

3

Metal-deficient SOD1 in amyotrophic lateral sclerosis.

Hilton JB, White AR, Crouch PJ. Hilton JB, et al. J Mol Med (Berl). 2015 May;93(5):481-7. doi: 10.1007/s00109-015-1273-3. Epub 2015 Mar 11. J Mol Med (Berl). 2015. PMID: 25754173 Free PMC article. Review.

4

Endogenous Cu in the central nervous system fails to satiate the elevated requirement for Cu in a mutant SOD1 mouse model of ALS.

Hilton JB, White AR, Crouch PJ. Hilton JB, et al. Metallomics. 2016 Sep 1;8(9):1002-11. doi: 10.1039/c6mt00099a. Epub 2016 Jun 30. Metallomics. 2016. PMID: 27357743

5

The accumulation of enzymatically inactive cuproenzymes is a CNS-specific phenomenon of the SOD1^G37R mouse model of ALS and can be restored by overexpressing the human copper transporter hCTR1.

Hilton JB, Kysenius K, White AR, Crouch PJ. Hilton JB, et al. Exp Neurol. 2018 Sep;307:118-128. doi: 10.1016/j.expneurol.2018.06.006. Epub 2018 Jun 12. Exp Neurol. 2018. PMID: 29906423 Free article.

6

A versatile quantitative microdroplet elemental imaging method optimised for integration in biochemical workflows for low-volume samples.

Kysenius K, Paul B, Hilton JB, Liddell JR, Hare DJ, Crouch PJ. Kysenius K, et al. Among authors: hilton jb. Anal Bioanal Chem. 2019 Jan;411(3):603-616. doi: 10.1007/s00216-018-1362-6. Epub 2018 Sep 15. Anal Bioanal Chem. 2019. PMID: 30218126

7

Anatomical redistribution of endogenous copper in embryonic mice overexpressing SOD1.

Kysenius K, Hilton JB, Paul B, Hare DJ, Crouch PJ. Kysenius K, et al. Among authors: hilton jb. Metallomics. 2019 Jan 23;11(1):141-150. doi: 10.1039/c8mt00242h. Metallomics. 2019. PMID: 30255176

8

Superoxide Dismutase 1 in Health and Disease: How a Frontline Antioxidant Becomes Neurotoxic.

Trist BG, Hilton JB, Hare DJ, Crouch PJ, Double KL. Trist BG, et al. Among authors: hilton jb. Angew Chem Int Ed Engl. 2021 Apr 19;60(17):9215-9246. doi: 10.1002/anie.202000451. Epub 2020 Nov 19. Angew Chem Int Ed Engl. 2021. PMID: 32144830 Free PMC article. Review.

9

TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.

Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D, Balka KR, Calleja DJ, Moghaddas F, Ni E, McLean CA, Samson AL, Tyebji S, Tonkin CJ, Bye CR, Turner BJ, Pepin G, Gantier MP, Rogers KL, McArthur K, Crouch PJ, Masters SL. Yu CH, et al. Among authors: hilton jb. Cell. 2020 Oct 29;183(3):636-649.e18. doi: 10.1016/j.cell.2020.09.020. Epub 2020 Oct 7. Cell. 2020. PMID: 33031745 Free PMC article.

10

Copper-ATSM as a Treatment for ALS: Support from Mutant SOD1 Models and Beyond.

Nikseresht S, Hilton JBW, Kysenius K, Liddell JR, Crouch PJ. Nikseresht S, et al. Among authors: hilton jbw. Life (Basel). 2020 Nov 4;10(11):271. doi: 10.3390/life10110271. Life (Basel). 2020. PMID: 33158182 Free PMC article. Review.

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