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Trithorax complex component Menin controls differentiation and maintenance of T helper 17 cells.
Watanabe Y, Onodera A, Kanai U, Ichikawa T, Obata-Ninomiya K, Wada T, Kiuchi M, Iwamura C, Tumes DJ, Shinoda K, Yagi R, Motohashi S, Hirahara K, Nakayama T. Watanabe Y, et al. Among authors: hirahara k. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12829-34. doi: 10.1073/pnas.1321245111. Epub 2014 Aug 18. Proc Natl Acad Sci U S A. 2014. PMID: 25136117 Free PMC article.
Bmi1 regulates memory CD4 T cell survival via repression of the Noxa gene.
Yamashita M, Kuwahara M, Suzuki A, Hirahara K, Shinnaksu R, Hosokawa H, Hasegawa A, Motohashi S, Iwama A, Nakayama T. Yamashita M, et al. Among authors: hirahara k. J Exp Med. 2008 May 12;205(5):1109-20. doi: 10.1084/jem.20072000. Epub 2008 Apr 14. J Exp Med. 2008. PMID: 18411339 Free PMC article.
Gata3/Ruvbl2 complex regulates T helper 2 cell proliferation via repression of Cdkn2c expression.
Hosokawa H, Tanaka T, Kato M, Shinoda K, Tohyama H, Hanazawa A, Tamaki Y, Hirahara K, Yagi R, Sakikawa I, Morita A, Nagira M, Poyurovsky MV, Suzuki Y, Motohashi S, Nakayama T. Hosokawa H, et al. Among authors: hirahara k. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18626-31. doi: 10.1073/pnas.1311100110. Epub 2013 Oct 28. Proc Natl Acad Sci U S A. 2013. PMID: 24167278 Free PMC article.
Pathogenic memory type Th2 cells in allergic inflammation.
Endo Y, Hirahara K, Yagi R, Tumes DJ, Nakayama T. Endo Y, et al. Among authors: hirahara k. Trends Immunol. 2014 Feb;35(2):69-78. doi: 10.1016/j.it.2013.11.003. Epub 2013 Dec 11. Trends Immunol. 2014. PMID: 24332592 Review.
Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.
Hirahara K, Onodera A, Villarino AV, Bonelli M, Sciumè G, Laurence A, Sun HW, Brooks SR, Vahedi G, Shih HY, Gutierrez-Cruz G, Iwata S, Suzuki R, Mikami Y, Okamoto Y, Nakayama T, Holland SM, Hunter CA, Kanno Y, O'Shea JJ. Hirahara K, et al. Immunity. 2015 May 19;42(5):877-89. doi: 10.1016/j.immuni.2015.04.014. Immunity. 2015. PMID: 25992861 Free PMC article.
236 results