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Immunochip analyses identify a novel risk locus for primary biliary cirrhosis at 13q14, multiple independent associations at four established risk loci and epistasis between 1p31 and 7q32 risk variants.
Juran BD, Hirschfield GM, Invernizzi P, Atkinson EJ, Li Y, Xie G, Kosoy R, Ransom M, Sun Y, Bianchi I, Schlicht EM, Lleo A, Coltescu C, Bernuzzi F, Podda M, Lammert C, Shigeta R, Chan LL, Balschun T, Marconi M, Cusi D, Heathcote EJ, Mason AL, Myers RP, Milkiewicz P, Odin JA, Luketic VA, Bacon BR, Bodenheimer HC Jr, Liakina V, Vincent C, Levy C, Franke A, Gregersen PK, Bossa F, Gershwin ME, deAndrade M, Amos CI; Italian PBC Genetics Study Group; Lazaridis KN, Seldin MF, Siminovitch KA. Juran BD, et al. Among authors: hirschfield gm. Hum Mol Genet. 2012 Dec 1;21(23):5209-21. doi: 10.1093/hmg/dds359. Epub 2012 Aug 29. Hum Mol Genet. 2012. PMID: 22936693 Free PMC article.
Primary biliary cirrhosis: the future.
Hirschfield GM, Heathcote EJ. Hirschfield GM, et al. Clin Liver Dis. 2008 May;12(2):473-9; xi. doi: 10.1016/j.cld.2008.02.002. Clin Liver Dis. 2008. PMID: 18456192 Review.
CTLA4/ICOS gene variants and haplotypes are associated with rheumatoid arthritis and primary biliary cirrhosis in the Canadian population.
Walker EJ, Hirschfield GM, Xu C, Lu Y, Liu X, Lu Y, Coltescu C, Wang K, Newman WG, Bykerk V, Keystone EC, Mosher D, Amos CI, Heathcote EJ, Siminovitch KA. Walker EJ, et al. Among authors: hirschfield gm. Arthritis Rheum. 2009 Apr;60(4):931-7. doi: 10.1002/art.24412. Arthritis Rheum. 2009. PMID: 19333938 Free article.
Cholestasis and cholestatic syndromes.
Hirschfield GM, Heathcote EJ. Hirschfield GM, et al. Curr Opin Gastroenterol. 2009 May;25(3):175-9. doi: 10.1097/mog.0b013e32832914b4. Curr Opin Gastroenterol. 2009. PMID: 19396955 Review.
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants.
Hirschfield GM, Liu X, Xu C, Lu Y, Xie G, Lu Y, Gu X, Walker EJ, Jing K, Juran BD, Mason AL, Myers RP, Peltekian KM, Ghent CN, Coltescu C, Atkinson EJ, Heathcote EJ, Lazaridis KN, Amos CI, Siminovitch KA. Hirschfield GM, et al. N Engl J Med. 2009 Jun 11;360(24):2544-55. doi: 10.1056/NEJMoa0810440. Epub 2009 May 20. N Engl J Med. 2009. PMID: 19458352 Free PMC article.
332 results