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A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human topoisomerase IIα.
Sandhaus S, Taylor R, Edwards T, Huddleston A, Wooten Y, Venkatraman R, Weber RT, González-Sarrías A, Martin PM, Cagle P, Tse-Dinh YC, Beebe SJ, Seeram N, Holder AA. Sandhaus S, et al. Among authors: holder aa. Inorg Chem Commun. 2016 Feb;64:45-49. doi: 10.1016/j.inoche.2015.12.013. Inorg Chem Commun. 2016. PMID: 26752972 Free PMC article.
Synthesis, characterization, and preliminary in vitro studies of vanadium(IV) complexes with a Schiff base and thiosemicarbazones as mixed-ligands.
Lewis NA, Liu F, Seymour L, Magnusen A, Erves TR, Arca JF, Beckford FA, Venkatraman R, González-Sarrías A, Fronczek FR, Vanderveer DG, Seeram NP, Liu A, Jarrett WL, Holder AA. Lewis NA, et al. Among authors: holder aa. Eur J Inorg Chem. 2012 Feb 1;2012(4):664-677. doi: 10.1002/ejic.201100898. Eur J Inorg Chem. 2012. PMID: 23904789 Free PMC article.
Synthesis, characterization, DNA binding, topoisomerase inhibition, and apoptosis induction studies of a novel cobalt(III) complex with a thiosemicarbazone ligand.
Beebe SJ, Celestine MJ, Bullock JL, Sandhaus S, Arca JF, Cropek DM, Ludvig TA, Foster SR, Clark JS, Beckford FA, Tano CM, Tonsel-White EA, Gurung RK, Stankavich CE, Tse-Dinh YC, Jarrett WL, Holder AA. Beebe SJ, et al. Among authors: holder aa. J Inorg Biochem. 2020 Feb;203:110907. doi: 10.1016/j.jinorgbio.2019.110907. Epub 2019 Nov 2. J Inorg Biochem. 2020. PMID: 31715377 Free PMC article.
Highly potent anti-proliferative effects of a gallium(III) complex with 7-chloroquinoline thiosemicarbazone as a ligand: synthesis, cytotoxic and antimalarial evaluation.
Kumar K, Schniper S, González-Sarrías A, Holder AA, Sanders N, Sullivan D, Jarrett WL, Davis K, Bai F, Seeram NP, Kumar V. Kumar K, et al. Among authors: holder aa. Eur J Med Chem. 2014 Oct 30;86:81-6. doi: 10.1016/j.ejmech.2014.08.054. Epub 2014 Aug 16. Eur J Med Chem. 2014. PMID: 25147149
Coordination of different ligands to copper(II) and cobalt(III) metal centers enhances Zika virus and dengue virus loads in both arthropod cells and human keratinocytes.
Dutta S, Celestine MJ, Khanal S, Huddleston A, Simms C, Arca JF, Mitra A, Heller L, Kraj PJ, Ledizet M, Anderson JF, Neelakanta G, Holder AA, Sultana H. Dutta S, et al. Among authors: holder aa. Biochim Biophys Acta Gen Subj. 2018 Jan;1862(1):40-50. doi: 10.1016/j.bbagen.2017.10.004. Epub 2017 Oct 13. Biochim Biophys Acta Gen Subj. 2018. PMID: 29030319
Preliminary anti-cancer photodynamic therapeutic in vitro studies with mixed-metal binuclear ruthenium(II)-vanadium(IV) complexes.
Holder AA, Taylor P, Magnusen AR, Moffett ET, Meyer K, Hong Y, Ramsdale SE, Gordon M, Stubbs J, Seymour LA, Acharya D, Weber RT, Smith PF, Dismukes GC, Ji P, Menocal L, Bai F, Williams JL, Cropek DM, Jarrett WL. Holder AA, et al. Dalton Trans. 2013 Sep 7;42(33):11881-99. doi: 10.1039/c3dt50547b. Dalton Trans. 2013. PMID: 23783642 Free PMC article.
336 results