Hollingsworth LR - Search Results

1

NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks.

David L, Borges JP, Hollingsworth LR, Volchuk A, Jansen I, Garlick E, Steinberg BE, Wu H. David L, et al. Among authors: hollingsworth lr. Cell. 2024 Apr 25;187(9):2224-2235.e16. doi: 10.1016/j.cell.2024.03.008. Epub 2024 Apr 12. Cell. 2024. PMID: 38614101

2

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.

Wang Y, Hollingsworth LR, Sangaré LO, Paredes-Santos TC, Krishnamurthy S, Penn BH, Wu H, Saeij JPJ. Wang Y, et al. Among authors: hollingsworth lr. bioRxiv [Preprint]. 2023 Dec 14:2023.12.13.571530. doi: 10.1101/2023.12.13.571530. bioRxiv. 2023. PMID: 38168400 Free PMC article. Updated. Preprint.

3

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.

Wang Y, Hollingsworth LR, Sangaré LO, Paredes-Santos TC, Krishnamurthy S, Penn BH, Wu H, Saeij JPJ. Wang Y, et al. Among authors: hollingsworth lr. mBio. 2024 Mar 13;15(3):e0330223. doi: 10.1128/mbio.03302-23. Epub 2024 Feb 20. mBio. 2024. PMID: 38376248 Free PMC article.

4

Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists.

Hollingsworth LR, Veeraraghavan P, Paulo JA, Harper JW, Rauch I. Hollingsworth LR, et al. bioRxiv [Preprint]. 2024 Apr 20:2024.04.19.590338. doi: 10.1101/2024.04.19.590338. bioRxiv. 2024. PMID: 38659763 Free PMC article. Preprint.

5

Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.

Sharif H, Hollingsworth LR, Griswold AR, Hsiao JC, Wang Q, Bachovchin DA, Wu H. Sharif H, et al. Among authors: hollingsworth lr. Immunity. 2021 Jul 13;54(7):1392-1404.e10. doi: 10.1016/j.immuni.2021.04.024. Epub 2021 May 20. Immunity. 2021. PMID: 34019797 Free PMC article.

6

DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation.

Hollingsworth LR, Sharif H, Griswold AR, Fontana P, Mintseris J, Dagbay KB, Paulo JA, Gygi SP, Bachovchin DA, Wu H. Hollingsworth LR, et al. Nature. 2021 Apr;592(7856):778-783. doi: 10.1038/s41586-021-03350-4. Epub 2021 Mar 17. Nature. 2021. PMID: 33731932 Free PMC article.

7

FDA-approved disulfiram inhibits pyroptosis by blocking gasdermin D pore formation.

Hu JJ, Liu X, Xia S, Zhang Z, Zhang Y, Zhao J, Ruan J, Luo X, Lou X, Bai Y, Wang J, Hollingsworth LR, Magupalli VG, Zhao L, Luo HR, Kim J, Lieberman J, Wu H. Hu JJ, et al. Among authors: hollingsworth lr. Nat Immunol. 2020 Jul;21(7):736-745. doi: 10.1038/s41590-020-0669-6. Epub 2020 May 4. Nat Immunol. 2020. PMID: 32367036 Free PMC article.

8

Molecular evolution of genes encoding allergen proteins in the peanuts genus Arachis: Structural and functional implications.

Hilu KW, Friend SA, Vallanadu V, Brown AM, Hollingsworth LR 4th, Bevan DR. Hilu KW, et al. Among authors: hollingsworth lr 4th. PLoS One. 2019 Nov 1;14(11):e0222440. doi: 10.1371/journal.pone.0222440. eCollection 2019. PLoS One. 2019. PMID: 31675366 Free PMC article.

9

Mechanism and Regulation of Gasdermin-Mediated Cell Death.

Xia S, Hollingsworth LR 4th, Wu H. Xia S, et al. Among authors: hollingsworth lr 4th. Cold Spring Harb Perspect Biol. 2020 Mar 2;12(3):a036400. doi: 10.1101/cshperspect.a036400. Cold Spring Harb Perspect Biol. 2020. PMID: 31451512 Free PMC article. Review.

10

HIV-1 Env gp41 Transmembrane Domain Dynamics Are Modulated by Lipid, Water, and Ion Interactions.

Hollingsworth LR 4th, Lemkul JA, Bevan DR, Brown AM. Hollingsworth LR 4th, et al. Biophys J. 2018 Jul 3;115(1):84-94. doi: 10.1016/j.bpj.2018.05.022. Biophys J. 2018. PMID: 29972814 Free PMC article.

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