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Monocarboxylate transporter MCT1 is a target for immunosuppression.
Nat Chem Biol. 2005 Dec;1(7):371-6. doi: 10.1038/nchembio744.
Nat Chem Biol. 2005.
PMID: 16370372
The specific monocarboxylate transporter-1 (MCT-1) inhibitor, AR-C117977, induces donor-specific suppression, reducing acute and chronic allograft rejection in the rat.
Ekberg H, Qi Z, Pahlman C, Veress B, Bundick RV, Craggs RI, Holness E, Edwards S, Murray CM, Ferguson D, Kerry PJ, Wilson E, Donald DK.
Ekberg H, et al. Among authors: holness e.
Transplantation. 2007 Nov 15;84(9):1191-9. doi: 10.1097/01.tp.0000287541.53389.be.
Transplantation. 2007.
PMID: 17998876
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The effect of cyclosporin A, FK506, and rapamycin on the murine chronic graft-versus-host response--an in vivo model of Th2-like activity.
Bundick RV, Craggs RI, Holness E.
Bundick RV, et al. Among authors: holness e.
Clin Exp Immunol. 1995 Mar;99(3):467-72. doi: 10.1111/j.1365-2249.1995.tb05574.x.
Clin Exp Immunol. 1995.
PMID: 7533681
Free PMC article.
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Biological characterization of a novel class of toll-like receptor 7 agonists designed to have reduced systemic activity.
Biffen M, Matsui H, Edwards S, Leishman AJ, Eiho K, Holness E, Satterthwaite G, Doyle I, Wada H, Fraser NJ, Hawkins SL, Aoki M, Tomizawa H, Benjamin AD, Takaku H, McInally T, Murray CM.
Biffen M, et al. Among authors: holness e.
Br J Pharmacol. 2012 May;166(2):573-86. doi: 10.1111/j.1476-5381.2011.01790.x.
Br J Pharmacol. 2012.
PMID: 22122192
Free PMC article.
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[The syndrome of renal and pulmonary vasculitis with positive neutrophil anticytoplasmic antibodies and antibasement membrane antibodies. A case report].
Bértoli F, Aguilar R, Solís D, de Holness E, Espino M.
Bértoli F, et al. Among authors: de holness e.
Rev Med Panama. 1994 May;19(2):92-100.
Rev Med Panama. 1994.
PMID: 7991808
Review.
Spanish.
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