Holstege H - Search Results

1

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.

Holstege H, Horlings HM, Velds A, Langerød A, Børresen-Dale AL, van de Vijver MJ, Nederlof PM, Jonkers J. Holstege H, et al. BMC Cancer. 2010 Nov 30;10:654. doi: 10.1186/1471-2407-10-654. BMC Cancer. 2010. PMID: 21118481 Free PMC article.

2

A whole-genome mouse BAC microarray with 1-Mb resolution for analysis of DNA copy number changes by array comparative genomic hybridization.

Chung YJ, Jonkers J, Kitson H, Fiegler H, Humphray S, Scott C, Hunt S, Yu Y, Nishijima I, Velds A, Holstege H, Carter N, Bradley A. Chung YJ, et al. Among authors: holstege h. Genome Res. 2004 Jan;14(1):188-96. doi: 10.1101/gr.1878804. Genome Res. 2004. PMID: 14707179 Free PMC article.

3

Human and mouse oligonucleotide-based array CGH.

van den Ijssel P, Tijssen M, Chin SF, Eijk P, Carvalho B, Hopmans E, Holstege H, Bangarusamy DK, Jonkers J, Meijer GA, Caldas C, Ylstra B. van den Ijssel P, et al. Among authors: holstege h. Nucleic Acids Res. 2005 Dec 16;33(22):e192. doi: 10.1093/nar/gni191. Nucleic Acids Res. 2005. PMID: 16361265 Free PMC article.

4

Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease.

Lechel A, Holstege H, Begus Y, Schienke A, Kamino K, Lehmann U, Kubicka S, Schirmacher P, Jonkers J, Rudolph KL. Lechel A, et al. Among authors: holstege h. Gastroenterology. 2007 Apr;132(4):1465-75. doi: 10.1053/j.gastro.2007.01.045. Epub 2007 Jan 26. Gastroenterology. 2007. PMID: 17433324

5

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.

Liu X, Holstege H, van der Gulden H, Treur-Mulder M, Zevenhoven J, Velds A, Kerkhoven RM, van Vliet MH, Wessels LF, Peterse JL, Berns A, Jonkers J. Liu X, et al. Among authors: holstege h. Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12111-6. doi: 10.1073/pnas.0702969104. Epub 2007 Jul 11. Proc Natl Acad Sci U S A. 2007. PMID: 17626182 Free PMC article.

6

Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data.

Klijn C, Holstege H, de Ridder J, Liu X, Reinders M, Jonkers J, Wessels L. Klijn C, et al. Among authors: holstege h. Nucleic Acids Res. 2008 Feb;36(2):e13. doi: 10.1093/nar/gkm1143. Epub 2008 Jan 10. Nucleic Acids Res. 2008. PMID: 18187509 Free PMC article.

7

Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.

Evers B, Drost R, Schut E, de Bruin M, van der Burg E, Derksen PW, Holstege H, Liu X, van Drunen E, Beverloo HB, Smith GC, Martin NM, Lau A, O'Connor MJ, Jonkers J. Evers B, et al. Among authors: holstege h. Clin Cancer Res. 2008 Jun 15;14(12):3916-25. doi: 10.1158/1078-0432.CCR-07-4953. Clin Cancer Res. 2008. PMID: 18559613 Free article.

8

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

Holstege H, Joosse SA, van Oostrom CT, Nederlof PM, de Vries A, Jonkers J. Holstege H, et al. Cancer Res. 2009 Apr 15;69(8):3625-33. doi: 10.1158/0008-5472.CAN-08-3426. Epub 2009 Mar 31. Cancer Res. 2009. PMID: 19336573

9

A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors.

Evers B, Schut E, van der Burg E, Braumuller TM, Egan DA, Holstege H, Edser P, Adams DJ, Wade-Martins R, Bouwman P, Jonkers J. Evers B, et al. Among authors: holstege h. Clin Cancer Res. 2010 Jan 1;16(1):99-108. doi: 10.1158/1078-0432.CCR-09-2434. Epub 2009 Dec 15. Clin Cancer Res. 2010. PMID: 20008842 Free PMC article.

10

BRD7 is a candidate tumour suppressor gene required for p53 function.

Drost J, Mantovani F, Tocco F, Elkon R, Comel A, Holstege H, Kerkhoven R, Jonkers J, Voorhoeve PM, Agami R, Del Sal G. Drost J, et al. Among authors: holstege h. Nat Cell Biol. 2010 Apr;12(4):380-9. doi: 10.1038/ncb2038. Epub 2010 Mar 14. Nat Cell Biol. 2010. PMID: 20228809

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