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Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver.
Ruiz R, Jideonwo V, Ahn M, Surendran S, Tagliabracci VS, Hou Y, Gamble A, Kerner J, Irimia-Dominguez JM, Puchowicz MA, DePaoli-Roach A, Hoppel C, Roach P, Morral N. Ruiz R, et al. Among authors: hoppel c. J Biol Chem. 2014 Feb 28;289(9):5510-7. doi: 10.1074/jbc.M113.541110. Epub 2014 Jan 7. J Biol Chem. 2014. PMID: 24398675 Free PMC article.
Mutations in the MPV17 gene are responsible for rapidly progressive liver failure in infancy.
Wong LJ, Brunetti-Pierri N, Zhang Q, Yazigi N, Bove KE, Dahms BB, Puchowicz MA, Gonzalez-Gomez I, Schmitt ES, Truong CK, Hoppel CL, Chou PC, Wang J, Baldwin EE, Adams D, Leslie N, Boles RG, Kerr DS, Craigen WJ. Wong LJ, et al. Among authors: hoppel cl. Hepatology. 2007 Oct;46(4):1218-27. doi: 10.1002/hep.21799. Hepatology. 2007. PMID: 17694548
Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism.
Prosdocimo DA, Anand P, Liao X, Zhu H, Shelkay S, Artero-Calderon P, Zhang L, Kirsh J, Moore D, Rosca MG, Vazquez E, Kerner J, Akat KM, Williams Z, Zhao J, Fujioka H, Tuschl T, Bai X, Schulze PC, Hoppel CL, Jain MK, Haldar SM. Prosdocimo DA, et al. J Biol Chem. 2014 Feb 28;289(9):5914-24. doi: 10.1074/jbc.M113.531384. Epub 2014 Jan 8. J Biol Chem. 2014. PMID: 24407292 Free PMC article.
352 results