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Page 1
High-level semi-synthetic production of the potent antimalarial artemisinin.
Paddon CJ, Westfall PJ, Pitera DJ, Benjamin K, Fisher K, McPhee D, Leavell MD, Tai A, Main A, Eng D, Polichuk DR, Teoh KH, Reed DW, Treynor T, Lenihan J, Fleck M, Bajad S, Dang G, Dengrove D, Diola D, Dorin G, Ellens KW, Fickes S, Galazzo J, Gaucher SP, Geistlinger T, Henry R, Hepp M, Horning T, Iqbal T, Jiang H, Kizer L, Lieu B, Melis D, Moss N, Regentin R, Secrest S, Tsuruta H, Vazquez R, Westblade LF, Xu L, Yu M, Zhang Y, Zhao L, Lievense J, Covello PS, Keasling JD, Reiling KK, Renninger NS, Newman JD. Paddon CJ, et al. Among authors: horning t. Nature. 2013 Apr 25;496(7446):528-32. doi: 10.1038/nature12051. Epub 2013 Apr 10. Nature. 2013. PMID: 23575629
Analysis of viral testing in nonacetaminophen pediatric acute liver failure.
Schwarz KB, Dell Olio D, Lobritto SJ, Lopez MJ, Rodriguez-Baez N, Yazigi NA, Belle SH, Zhang S, Squires RH; Pediatric Acute Liver Failure Study Group. Schwarz KB, et al. J Pediatr Gastroenterol Nutr. 2014 Nov;59(5):616-23. doi: 10.1097/MPG.0000000000000512. J Pediatr Gastroenterol Nutr. 2014. PMID: 25340974 Free PMC article.
A Learning Collaborative Approach Increases Specificity of Diagnosis of Acute Liver Failure in Pediatric Patients.
Narkewicz MR, Horslen S, Hardison RM, Shneider BL, Rodriguez-Baez N, Alonso EM, Ng VL, Leonis MA, Loomes KM, Rudnick DA, Rosenthal P, Romero R, Subbarao GC, Li R, Belle SH, Squires RH; Pediatric Acute Liver Failure Study Group. Narkewicz MR, et al. Clin Gastroenterol Hepatol. 2018 Nov;16(11):1801-1810.e3. doi: 10.1016/j.cgh.2018.04.050. Epub 2018 Apr 30. Clin Gastroenterol Hepatol. 2018. PMID: 29723692 Free PMC article.
Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin.
Westfall PJ, Pitera DJ, Lenihan JR, Eng D, Woolard FX, Regentin R, Horning T, Tsuruta H, Melis DJ, Owens A, Fickes S, Diola D, Benjamin KR, Keasling JD, Leavell MD, McPhee DJ, Renninger NS, Newman JD, Paddon CJ. Westfall PJ, et al. Among authors: horning t. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):E111-8. doi: 10.1073/pnas.1110740109. Epub 2012 Jan 12. Proc Natl Acad Sci U S A. 2012. PMID: 22247290 Free PMC article.