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A meta-analysis of genome-wide association studies of epigenetic age acceleration.
Gibson J, Russ TC, Clarke TK, Howard DM, Hillary RF, Evans KL, Walker RM, Bermingham ML, Morris SW, Campbell A, Hayward C, Murray AD, Porteous DJ, Horvath S, Lu AT, McIntosh AM, Whalley HC, Marioni RE. Gibson J, et al. Among authors: horvath s. PLoS Genet. 2019 Nov 18;15(11):e1008104. doi: 10.1371/journal.pgen.1008104. eCollection 2019 Nov. PLoS Genet. 2019. PMID: 31738745 Free PMC article.
Two commonly used measures, derived from DNA methylation, are Horvath-based (Horvath-EAA) and Hannum-based (Hannum-EAA) epigenetic age acceleration. ...We identified ten independent SNPs associated with Horvath-EAA, five of which are novel. We also report 21 …
Two commonly used measures, derived from DNA methylation, are Horvath-based (Horvath-EAA) and Hannum-based (Hannum-EAA) epigen …
Epigenetic predictor of age.
Bocklandt S, Lin W, Sehl ME, Sánchez FJ, Sinsheimer JS, Horvath S, Vilain E. Bocklandt S, et al. Among authors: horvath s. PLoS One. 2011;6(6):e14821. doi: 10.1371/journal.pone.0014821. Epub 2011 Jun 22. PLoS One. 2011. PMID: 21731603 Free PMC article.
An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy.
Li Y, Chen JA, Sears RL, Gao F, Klein ED, Karydas A, Geschwind MD, Rosen HJ, Boxer AL, Guo W, Pellegrini M, Horvath S, Miller BL, Geschwind DH, Coppola G. Li Y, et al. Among authors: horvath s. PLoS Genet. 2014 Mar 6;10(3):e1004211. doi: 10.1371/journal.pgen.1004211. eCollection 2014 Mar. PLoS Genet. 2014. PMID: 24603599 Free PMC article.
The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936.
Marioni RE, Shah S, McRae AF, Ritchie SJ, Muniz-Terrera G, Harris SE, Gibson J, Redmond P, Cox SR, Pattie A, Corley J, Taylor A, Murphy L, Starr JM, Horvath S, Visscher PM, Wray NR, Deary IJ. Marioni RE, et al. Among authors: horvath s. Int J Epidemiol. 2015 Aug;44(4):1388-96. doi: 10.1093/ije/dyu277. Epub 2015 Jan 22. Int J Epidemiol. 2015. PMID: 25617346 Free PMC article.
DNA methylation age of blood predicts all-cause mortality in later life.
Marioni RE, Shah S, McRae AF, Chen BH, Colicino E, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Feinberg AP, Fallin MD, Multhaup ML, Jaffe AE, Joehanes R, Schwartz J, Just AC, Lunetta KL, Murabito JM, Starr JM, Horvath S, Baccarelli AA, Levy D, Visscher PM, Wray NR, Deary IJ. Marioni RE, et al. Among authors: horvath s. Genome Biol. 2015 Jan 30;16(1):25. doi: 10.1186/s13059-015-0584-6. Genome Biol. 2015. PMID: 25633388 Free PMC article.
Accelerated epigenetic aging in Down syndrome.
Horvath S, Garagnani P, Bacalini MG, Pirazzini C, Salvioli S, Gentilini D, Di Blasio AM, Giuliani C, Tung S, Vinters HV, Franceschi C. Horvath S, et al. Aging Cell. 2015 Jun;14(3):491-5. doi: 10.1111/acel.12325. Epub 2015 Feb 9. Aging Cell. 2015. PMID: 25678027 Free PMC article.
Acceleration of age-associated methylation patterns in HIV-1-infected adults.
Rickabaugh TM, Baxter RM, Sehl M, Sinsheimer JS, Hultin PM, Hultin LE, Quach A, Martínez-Maza O, Horvath S, Vilain E, Jamieson BD. Rickabaugh TM, et al. Among authors: horvath s. PLoS One. 2015 Mar 25;10(3):e0119201. doi: 10.1371/journal.pone.0119201. eCollection 2015. PLoS One. 2015. PMID: 25807146 Free PMC article.
Epigenetic age analysis of children who seem to evade aging.
Walker RF, Liu JS, Peters BA, Ritz BR, Wu T, Ophoff RA, Horvath S. Walker RF, et al. Among authors: horvath s. Aging (Albany NY). 2015 May;7(5):334-9. doi: 10.18632/aging.100744. Aging (Albany NY). 2015. PMID: 25991677 Free PMC article.
1,277 results