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Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.
Engelen E, Akinci U, Bryne JC, Hou J, Gontan C, Moen M, Szumska D, Kockx C, van Ijcken W, Dekkers DH, Demmers J, Rijkers EJ, Bhattacharya S, Philipsen S, Pevny LH, Grosveld FG, Rottier RJ, Lenhard B, Poot RA. Engelen E, et al. Among authors: hou j. Nat Genet. 2011 Jun;43(6):607-11. doi: 10.1038/ng.825. Epub 2011 May 1. Nat Genet. 2011. PMID: 21532573
Genome-wide DNA methylation profiling of non-small cell lung carcinomas.
Carvalho RH, Haberle V, Hou J, van Gent T, Thongjuea S, van Ijcken W, Kockx C, Brouwer R, Rijkers E, Sieuwerts A, Foekens J, van Vroonhoven M, Aerts J, Grosveld F, Lenhard B, Philipsen S. Carvalho RH, et al. Among authors: hou j. Epigenetics Chromatin. 2012 Jun 22;5(1):9. doi: 10.1186/1756-8935-5-9. Epigenetics Chromatin. 2012. PMID: 22726460 Free PMC article.
The DNA binding factor Hmg20b is a repressor of erythroid differentiation.
Esteghamat F, van Dijk TB, Braun H, Dekker S, van der Linden R, Hou J, Fanis P, Demmers J, van IJcken W, Ozgür Z, Horos R, Pourfarzad F, von Lindern M, Philipsen S. Esteghamat F, et al. Among authors: hou j. Haematologica. 2011 Sep;96(9):1252-60. doi: 10.3324/haematol.2011.045211. Epub 2011 May 23. Haematologica. 2011. PMID: 21606163 Free PMC article.
Hydroxyurea responsiveness in β-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity.
Pourfarzad F, von Lindern M, Azarkeivan A, Hou J, Kia SK, Esteghamat F, van Ijcken W, Philipsen S, Najmabadi H, Grosveld F. Pourfarzad F, et al. Among authors: hou j. Haematologica. 2013 May;98(5):696-704. doi: 10.3324/haematol.2012.074492. Epub 2012 Oct 25. Haematologica. 2013. PMID: 23100274 Free PMC article.
Transcription factor Sp3 knockout mice display serious cardiac malformations.
van Loo PF, Mahtab EA, Wisse LJ, Hou J, Grosveld F, Suske G, Philipsen S, Gittenberger-de Groot AC. van Loo PF, et al. Among authors: hou j. Mol Cell Biol. 2007 Dec;27(24):8571-82. doi: 10.1128/MCB.01350-07. Epub 2007 Oct 8. Mol Cell Biol. 2007. PMID: 17923686 Free PMC article.
KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in β-hemoglobinopathy patients.
Borg J, Phylactides M, Bartsakoulia M, Tafrali C, Lederer C, Felice AE, Papachatzopoulou A, Kourakli A, Stavrou EF, Christou S, Hou J, Karkabouna S, Lappa-Manakou C, Ozgur Z, van Ijcken W, von Lindern M, Grosveld FG, Georgitsi M, Kleanthous M, Philipsen S, Patrinos GP. Borg J, et al. Among authors: hou j. Pharmacogenomics. 2012 Oct;13(13):1487-500. doi: 10.2217/pgs.12.125. Pharmacogenomics. 2012. PMID: 23057549
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