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Orchestrating high-throughput genomic analysis with Bioconductor.
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Huber W, et al. Nat Methods. 2015 Feb;12(2):115-21. doi: 10.1038/nmeth.3252. Nat Methods. 2015. PMID: 25633503 Free PMC article. Review.
Bioconductor: open software development for computational biology and bioinformatics.
Gentleman RC, Carey VJ, Bates DM, Bolstad B, Dettling M, Dudoit S, Ellis B, Gautier L, Ge Y, Gentry J, Hornik K, Hothorn T, Huber W, Iacus S, Irizarry R, Leisch F, Li C, Maechler M, Rossini AJ, Sawitzki G, Smith C, Smyth G, Tierney L, Yang JY, Zhang J. Gentleman RC, et al. Among authors: huber w. Genome Biol. 2004;5(10):R80. doi: 10.1186/gb-2004-5-10-r80. Epub 2004 Sep 15. Genome Biol. 2004. PMID: 15461798 Free PMC article.
Functional profiling: from microarrays via cell-based assays to novel tumor relevant modulators of the cell cycle.
Arlt D, Huber W, Liebel U, Schmidt C, Majety M, Sauermann M, Rosenfelder H, Bechtel S, Mehrle A, Bannasch D, Schupp I, Seiler M, Simpson JC, Hahne F, Moosmayer P, Ruschhaupt M, Guilleaume B, Wellenreuther R, Pepperkok R, Sültmann H, Poustka A, Wiemann S. Arlt D, et al. Among authors: huber w. Cancer Res. 2005 Sep 1;65(17):7733-42. doi: 10.1158/0008-5472.CAN-05-0642. Cancer Res. 2005. PMID: 16140941
The LIFEdb database in 2006.
Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S. Mehrle A, et al. Among authors: huber w. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D415-8. doi: 10.1093/nar/gkj139. Nucleic Acids Res. 2006. PMID: 16381901 Free PMC article.
Top-down standards will not serve systems biology.
Quackenbush J, Stoeckert C, Ball C, Brazma A, Gentleman R, Huber W, Irizarry R, Salit M, Sherlock G, Spellman P, Winegarden N. Quackenbush J, et al. Among authors: huber w. Nature. 2006 Mar 2;440(7080):24. doi: 10.1038/440024a. Nature. 2006. PMID: 16511469 No abstract available.
979 results