Hussein N - Search Results

1

Novel Chrysin-De-Allyl PAC-1 Hybrid Analogues as Anticancer Compounds: Design, Synthesis, and Biological Evaluation.

Al-Oudat BA, Ramapuram H, Malla S, Audat SA, Hussein N, Len JM, Kumari S, Bedi MF, Ashby CR Jr, Tiwari AK. Al-Oudat BA, et al. Among authors: hussein n. Molecules. 2020 Jul 4;25(13):3063. doi: 10.3390/molecules25133063. Molecules. 2020. PMID: 32635530 Free PMC article.

2

A Novel Dialkylamino-Functionalized Chalcone, DML6, Inhibits Cervical Cancer Cell Proliferation, In Vitro, via Induction of Oxidative Stress, Intrinsic Apoptosis and Mitotic Catastrophe.

Len JM, Hussein N, Malla S, Mcintosh K, Patidar R, Elangovan M, Chandrabose K, Moorthy NSHN, Pandey M, Raman D, Trivedi P, Tiwari AK. Len JM, et al. Among authors: hussein n. Molecules. 2021 Jul 11;26(14):4214. doi: 10.3390/molecules26144214. Molecules. 2021. PMID: 34299490 Free PMC article.

3

The role of endolysosomal trafficking in anticancer drug resistance.

Hussein NA, Malla S, Pasternak MA, Terrero D, Brown NG, Ashby CR Jr, Assaraf YG, Chen ZS, Tiwari AK. Hussein NA, et al. Drug Resist Updat. 2021 Jul;57:100769. doi: 10.1016/j.drup.2021.100769. Epub 2021 Jun 2. Drug Resist Updat. 2021. PMID: 34217999 Review.

4

Design and discovery of silybin analogues as antiproliferative compounds using a ring disjunctive - Based, natural product lead optimization approach.

Manivannan E, Amawi H, Hussein N, Karthikeyan C, Fetcenko A, Narayana Moorthy NSH, Trivedi P, Tiwari AK. Manivannan E, et al. Among authors: hussein n. Eur J Med Chem. 2017 Jun 16;133:365-378. doi: 10.1016/j.ejmech.2017.03.033. Epub 2017 Mar 22. Eur J Med Chem. 2017. PMID: 28411546

5

Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe.

Amawi H, Karthikeyan C, Pathak R, Hussein N, Christman R, Robey R, Ashby CR Jr, Trivedi P, Malhotra A, Tiwari AK. Amawi H, et al. Among authors: hussein n. Eur J Med Chem. 2017 Sep 29;138:1053-1065. doi: 10.1016/j.ejmech.2017.07.028. Epub 2017 Jul 20. Eur J Med Chem. 2017. PMID: 28759878

6

lH-Pyrazolo[3,4-b]quinolin-3-amine derivatives inhibit growth of colon cancer cells via apoptosis and sub G1 cell cycle arrest.

Karthikeyan C, Amawi H, Viana AG, Sanglard L, Hussein N, Saddler M, Ashby CR Jr, Moorthy NSHN, Trivedi P, Tiwari AK. Karthikeyan C, et al. Among authors: hussein n. Bioorg Med Chem Lett. 2018 Jul 15;28(13):2244-2249. doi: 10.1016/j.bmcl.2018.05.045. Epub 2018 May 24. Bioorg Med Chem Lett. 2018. PMID: 29853331

7

Bax/Tubulin/Epithelial-Mesenchymal Pathways Determine the Efficacy of Silybin Analog HM015k in Colorectal Cancer Cell Growth and Metastasis.

Amawi H, Hussein NA, Ashby CR Jr, Alnafisah R, Sanglard LM, Manivannan E, Karthikeyan C, Trivedi P, Eisenmann KM, Robey RW, Tiwari AK. Amawi H, et al. Front Pharmacol. 2018 May 23;9:520. doi: 10.3389/fphar.2018.00520. eCollection 2018. Front Pharmacol. 2018. PMID: 29875662 Free PMC article.

8

The dopamine D₃ receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines.

Hussein N, Amawi H, Karthikeyan C, Hall FS, Mittal R, Trivedi P, Ashby CR Jr, Tiwari AK. Hussein N, et al. Cancer Lett. 2017 Jun 28;396:167-180. doi: 10.1016/j.canlet.2017.03.015. Epub 2017 Mar 18. Cancer Lett. 2017. PMID: 28323029

9

Novel Thienopyrimidine Derivative, RP-010, Induces β-Catenin Fragmentation and Is Efficacious against Prostate Cancer Cells.

Amawi H, Hussein N, Boddu SHS, Karthikeyan C, Williams FE, Ashby CR Jr, Raman D, Trivedi P, Tiwari AK. Amawi H, et al. Among authors: hussein n. Cancers (Basel). 2019 May 23;11(5):711. doi: 10.3390/cancers11050711. Cancers (Basel). 2019. PMID: 31126091 Free PMC article.

10

HM015k, a Novel Silybin Derivative, Multi-Targets Metastatic Ovarian Cancer Cells and Is Safe in Zebrafish Toxicity Studies.

Amawi H, Hussein NA, Karthikeyan C, Manivannan E, Wisner A, Williams FE, Samuel T, Trivedi P, Ashby CR Jr, Tiwari AK. Amawi H, et al. Front Pharmacol. 2017 Aug 2;8:498. doi: 10.3389/fphar.2017.00498. eCollection 2017. Front Pharmacol. 2017. PMID: 28824426 Free PMC article.

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