Hussein NA - Search Results

1

The role of endolysosomal trafficking in anticancer drug resistance.

Hussein NA, Malla S, Pasternak MA, Terrero D, Brown NG, Ashby CR Jr, Assaraf YG, Chen ZS, Tiwari AK. Hussein NA, et al. Drug Resist Updat. 2021 Jul;57:100769. doi: 10.1016/j.drup.2021.100769. Epub 2021 Jun 2. Drug Resist Updat. 2021. PMID: 34217999 Review.

2

The dopamine D₃ receptor antagonists PG01037, NGB2904, SB277011A, and U99194 reverse ABCG2 transporter-mediated drug resistance in cancer cell lines.

Hussein N, Amawi H, Karthikeyan C, Hall FS, Mittal R, Trivedi P, Ashby CR Jr, Tiwari AK. Hussein N, et al. Cancer Lett. 2017 Jun 28;396:167-180. doi: 10.1016/j.canlet.2017.03.015. Epub 2017 Mar 18. Cancer Lett. 2017. PMID: 28323029

3

Novel Chrysin-De-Allyl PAC-1 Hybrid Analogues as Anticancer Compounds: Design, Synthesis, and Biological Evaluation.

Al-Oudat BA, Ramapuram H, Malla S, Audat SA, Hussein N, Len JM, Kumari S, Bedi MF, Ashby CR Jr, Tiwari AK. Al-Oudat BA, et al. Molecules. 2020 Jul 4;25(13):3063. doi: 10.3390/molecules25133063. Molecules. 2020. PMID: 32635530 Free PMC article.

4

Bax/Tubulin/Epithelial-Mesenchymal Pathways Determine the Efficacy of Silybin Analog HM015k in Colorectal Cancer Cell Growth and Metastasis.

Amawi H, Hussein NA, Ashby CR Jr, Alnafisah R, Sanglard LM, Manivannan E, Karthikeyan C, Trivedi P, Eisenmann KM, Robey RW, Tiwari AK. Amawi H, et al. Among authors: hussein na. Front Pharmacol. 2018 May 23;9:520. doi: 10.3389/fphar.2018.00520. eCollection 2018. Front Pharmacol. 2018. PMID: 29875662 Free PMC article.

5

Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe.

Amawi H, Karthikeyan C, Pathak R, Hussein N, Christman R, Robey R, Ashby CR Jr, Trivedi P, Malhotra A, Tiwari AK. Amawi H, et al. Eur J Med Chem. 2017 Sep 29;138:1053-1065. doi: 10.1016/j.ejmech.2017.07.028. Epub 2017 Jul 20. Eur J Med Chem. 2017. PMID: 28759878

6

lH-Pyrazolo[3,4-b]quinolin-3-amine derivatives inhibit growth of colon cancer cells via apoptosis and sub G1 cell cycle arrest.

Karthikeyan C, Amawi H, Viana AG, Sanglard L, Hussein N, Saddler M, Ashby CR Jr, Moorthy NSHN, Trivedi P, Tiwari AK. Karthikeyan C, et al. Bioorg Med Chem Lett. 2018 Jul 15;28(13):2244-2249. doi: 10.1016/j.bmcl.2018.05.045. Epub 2018 May 24. Bioorg Med Chem Lett. 2018. PMID: 29853331

7

Cariprazine, A Dopamine D₂/D₃ Receptor Partial Agonist, Modulates ABCG2-Mediated Multidrug Resistance in Cancer.

Hussein N, Ashby CR Jr, Amawi H, Nyinawabera A, Vij A, Khare VM, Karthikeyan C, Tiwari AK. Hussein N, et al. Cancers (Basel). 2018 Sep 4;10(9):308. doi: 10.3390/cancers10090308. Cancers (Basel). 2018. PMID: 30181510 Free PMC article.

8

Novel Thienopyrimidine Derivative, RP-010, Induces β-Catenin Fragmentation and Is Efficacious against Prostate Cancer Cells.

Amawi H, Hussein N, Boddu SHS, Karthikeyan C, Williams FE, Ashby CR Jr, Raman D, Trivedi P, Tiwari AK. Amawi H, et al. Cancers (Basel). 2019 May 23;11(5):711. doi: 10.3390/cancers11050711. Cancers (Basel). 2019. PMID: 31126091 Free PMC article.

9

HM015k, a Novel Silybin Derivative, Multi-Targets Metastatic Ovarian Cancer Cells and Is Safe in Zebrafish Toxicity Studies.

Amawi H, Hussein NA, Karthikeyan C, Manivannan E, Wisner A, Williams FE, Samuel T, Trivedi P, Ashby CR Jr, Tiwari AK. Amawi H, et al. Among authors: hussein na. Front Pharmacol. 2017 Aug 2;8:498. doi: 10.3389/fphar.2017.00498. eCollection 2017. Front Pharmacol. 2017. PMID: 28824426 Free PMC article.

10

Design and discovery of silybin analogues as antiproliferative compounds using a ring disjunctive - Based, natural product lead optimization approach.

Manivannan E, Amawi H, Hussein N, Karthikeyan C, Fetcenko A, Narayana Moorthy NSH, Trivedi P, Tiwari AK. Manivannan E, et al. Eur J Med Chem. 2017 Jun 16;133:365-378. doi: 10.1016/j.ejmech.2017.03.033. Epub 2017 Mar 22. Eur J Med Chem. 2017. PMID: 28411546

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