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Monocarboxylate transporter MCT1 is a target for immunosuppression.
Murray CM, Hutchinson R, Bantick JR, Belfield GP, Benjamin AD, Brazma D, Bundick RV, Cook ID, Craggs RI, Edwards S, Evans LR, Harrison R, Holness E, Jackson AP, Jackson CG, Kingston LP, Perry MW, Ross AR, Rugman PA, Sidhu SS, Sullivan M, Taylor-Fishwick DA, Walker PC, Whitehead YM, Wilkinson DJ, Wright A, Donald DK. Murray CM, et al. Among authors: hutchinson r. Nat Chem Biol. 2005 Dec;1(7):371-6. doi: 10.1038/nchembio744. Nat Chem Biol. 2005. PMID: 16370372
Potent blockers of the monocarboxylate transporter MCT1: novel immunomodulatory compounds.
Guile SD, Bantick JR, Cheshire DR, Cooper ME, Davis AM, Donald DK, Evans R, Eyssade C, Ferguson DD, Hill S, Hutchinson R, Ingall AH, Kingston LP, Martin I, Martin BP, Mohammed RT, Murray C, Perry MW, Reynolds RH, Thorne PV, Wilkinson DJ, Withnall J. Guile SD, et al. Among authors: hutchinson r. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2260-5. doi: 10.1016/j.bmcl.2006.01.024. Epub 2006 Feb 7. Bioorg Med Chem Lett. 2006. PMID: 16455256
738 results