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Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.
Innes H, Buch S, Hutchinson S, Guha IN, Morling JR, Barnes E, Irving W, Forrest E, Pedergnana V, Goldberg D, Aspinall E, Barclay S, Hayes PC, Dillon J, Nischalke HD, Lutz P, Spengler U, Fischer J, Berg T, Brosch M, Eyer F, Datz C, Mueller S, Peccerella T, Deltenre P, Marot A, Soyka M, McQuillin A, Morgan MY, Hampe J, Stickel F. Innes H, et al. Among authors: irving w. Gastroenterology. 2020 Oct;159(4):1276-1289.e7. doi: 10.1053/j.gastro.2020.06.014. Epub 2020 Jun 16. Gastroenterology. 2020. PMID: 32561361
'Favourable' IL28B polymorphisms are associated with a marked increase in baseline viral load in hepatitis C virus subtype 3a infection and do not predict a sustained virological response after 24 weeks of therapy.
Bucci C, von Delft A, Christian A, Flemming VM, Harrison A, Halliday J, Collier J, Manganis C, Klenerman P, Irving W, Barnes E. Bucci C, et al. Among authors: irving w. J Gen Virol. 2013 Jun;94(Pt 6):1259-1265. doi: 10.1099/vir.0.051052-0. Epub 2013 Mar 13. J Gen Virol. 2013. PMID: 23486666
Interferon-λ rs12979860 genotype and liver fibrosis in viral and non-viral chronic liver disease.
Eslam M, Hashem AM, Leung R, Romero-Gomez M, Berg T, Dore GJ, Chan HL, Irving WL, Sheridan D, Abate ML, Adams LA, Mangia A, Weltman M, Bugianesi E, Spengler U, Shaker O, Fischer J, Mollison L, Cheng W, Powell E, Nattermann J, Riordan S, McLeod D, Armstrong NJ, Douglas MW, Liddle C, Booth DR, George J, Ahlenstiel G; International Hepatitis C Genetics Consortium (IHCGC). Eslam M, et al. Among authors: irving wl. Nat Commun. 2015 Mar 5;6:6422. doi: 10.1038/ncomms7422. Nat Commun. 2015. PMID: 25740255 Free PMC article.
FibroGENE: A gene-based model for staging liver fibrosis.
Eslam M, Hashem AM, Romero-Gomez M, Berg T, Dore GJ, Mangia A, Chan HLY, Irving WL, Sheridan D, Abate ML, Adams LA, Weltman M, Bugianesi E, Spengler U, Shaker O, Fischer J, Mollison L, Cheng W, Nattermann J, Riordan S, Miele L, Kelaeng KS, Ampuero J, Ahlenstiel G, McLeod D, Powell E, Liddle C, Douglas MW, Booth DR, George J; International Liver Disease Genetics Consortium (ILDGC). Eslam M, et al. Among authors: irving wl. J Hepatol. 2016 Feb;64(2):390-398. doi: 10.1016/j.jhep.2015.11.008. Epub 2015 Dec 1. J Hepatol. 2016. PMID: 26592354 Free article.
Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes.
Eslam M, Mangia A, Berg T, Chan HL, Irving WL, Dore GJ, Abate ML, Bugianesi E, Adams LA, Najim MA, Miele L, Weltman M, Mollison L, Cheng W, Riordan S, Fischer J, Romero-Gomez M, Spengler U, Nattermann J, Rahme A, Sheridan D, Booth DR, McLeod D, Powell E, Liddle C, Douglas MW, van der Poorten D, George J; International Liver Disease Genetics Consortium. Eslam M, et al. Among authors: irving wl. Hepatology. 2016 Jul;64(1):34-46. doi: 10.1002/hep.28475. Epub 2016 Mar 30. Hepatology. 2016. PMID: 26822232 Free article.
MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C.
Thabet K, Asimakopoulos A, Shojaei M, Romero-Gomez M, Mangia A, Irving WL, Berg T, Dore GJ, Grønbæk H, Sheridan D, Abate ML, Bugianesi E, Weltman M, Mollison L, Cheng W, Riordan S, Fischer J, Spengler U, Nattermann J, Wahid A, Rojas A, White R, Douglas MW, McLeod D, Powell E, Liddle C, van der Poorten D, George J, Eslam M; International Liver Disease Genetics Consortium. Thabet K, et al. Among authors: irving wl. Nat Commun. 2016 Sep 15;7:12757. doi: 10.1038/ncomms12757. Nat Commun. 2016. PMID: 27630043 Free PMC article.
Cohort Profile: The Hepatitis C Virus (HCV) Research UK Clinical Database and Biobank.
McLauchlan J, Innes H, Dillon JF, Foster G, Holtham E, McDonald S, Wilkes B, Hutchinson SJ, Irving WL; HCV Research UK Steering Committee. McLauchlan J, et al. Among authors: irving wl. Int J Epidemiol. 2017 Oct 1;46(5):1391-1391h. doi: 10.1093/ije/dyw362. Int J Epidemiol. 2017. PMID: 28338838 Free PMC article. No abstract available.
IFN-λ3, not IFN-λ4, likely mediates IFNL3-IFNL4 haplotype-dependent hepatic inflammation and fibrosis.
Eslam M, McLeod D, Kelaeng KS, Mangia A, Berg T, Thabet K, Irving WL, Dore GJ, Sheridan D, Grønbæk H, Abate ML, Hartmann R, Bugianesi E, Spengler U, Rojas A, Booth DR, Weltman M, Mollison L, Cheng W, Riordan S, Mahajan H, Fischer J, Nattermann J, Douglas MW, Liddle C, Powell E, Romero-Gomez M, George J; International Liver Disease Genetics Consortium (ILDGC). Eslam M, et al. Among authors: irving wl. Nat Genet. 2017 May;49(5):795-800. doi: 10.1038/ng.3836. Epub 2017 Apr 10. Nat Genet. 2017. PMID: 28394349 Free article.
271 results