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Page 1
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.
Liu H, Irwanto A, Fu X, Yu G, Yu Y, Sun Y, Wang C, Wang Z, Okada Y, Low H, Li Y, Liany H, Chen M, Bao F, Li J, You J, Zhang Q, Liu J, Chu T, Andiappan AK, Wang N, Niu G, Liu D, Yu X, Zhang L, Tian H, Zhou G, Rotzschke O, Chen S, Zhang X, Liu J, Zhang F. Liu H, et al. Among authors: irwanto a. Nat Genet. 2015 Mar;47(3):267-71. doi: 10.1038/ng.3212. Epub 2015 Feb 2. Nat Genet. 2015. PMID: 25642632
A large-scale genome-wide association and meta-analysis identified four novel susceptibility loci for leprosy.
Wang Z, Sun Y, Fu X, Yu G, Wang C, Bao F, Yue Z, Li J, Sun L, Irwanto A, Yu Y, Chen M, Mi Z, Wang H, Huai P, Li Y, Du T, Yu W, Xia Y, Xiao H, You J, Li J, Yang Q, Wang N, Shang P, Niu G, Chi X, Wang X, Cao J, Cheng X, Liu H, Liu J, Zhang F. Wang Z, et al. Among authors: irwanto a. Nat Commun. 2016 Dec 15;7:13760. doi: 10.1038/ncomms13760. Nat Commun. 2016. PMID: 27976721 Free PMC article.
Genome-Wide Analysis of Protein-Coding Variants in Leprosy.
Liu H, Wang Z, Li Y, Yu G, Fu X, Wang C, Liu W, Yu Y, Bao F, Irwanto A, Liu J, Chu T, Andiappan AK, Maurer-Stroh S, Limviphuvadh V, Wang H, Mi Z, Sun Y, Sun L, Wang L, Wang C, You J, Li J, Foo JN, Liany H, Meah WY, Niu G, Yue Z, Zhao Q, Wang N, Yu M, Yu W, Cheng X, Khor CC, Sim KS, Aung T, Wang N, Wang D, Shi L, Ning Y, Zheng Z, Yang R, Li J, Yang J, Yan L, Shen J, Zhang G, Chen S, Liu J, Zhang F. Liu H, et al. Among authors: irwanto a. J Invest Dermatol. 2017 Dec;137(12):2544-2551. doi: 10.1016/j.jid.2017.08.004. Epub 2017 Aug 24. J Invest Dermatol. 2017. PMID: 28842327 Free article.
An association study of TOLL and CARD with leprosy susceptibility in Chinese population.
Liu H, Bao F, Irwanto A, Fu X, Lu N, Yu G, Yu Y, Sun Y, Low H, Li Y, Liany H, Yuan C, Li J, Liu J, Chen M, Liu H, Wang N, You J, Ma S, Niu G, Zhou Y, Chu T, Tian H, Chen S, Zhang X, Liu J, Zhang F. Liu H, et al. Among authors: irwanto a. Hum Mol Genet. 2013 Nov 1;22(21):4430-7. doi: 10.1093/hmg/ddt286. Epub 2013 Jun 19. Hum Mol Genet. 2013. PMID: 23784377 Free PMC article.
Evaluation of Prospective HLA-B*13:01 Screening to Prevent Dapsone Hypersensitivity Syndrome in Patients With Leprosy.
Liu H, Wang Z, Bao F, Wang C, Sun L, Zhang H, Yu G, Mi Z, Li J, Li L, Zhao Q, Yue Z, Zhao W, Yu W, Cao J, Xiong F, Wang Y, Chai Z, Cheng X, Zhang Y, Fu F, Lang X, Wang X, Irwanto A, Krismawati H, Fu X, Sun Y, You J, Liu J, Pan Q, Chu T, Liu D, Chen S, Shen J, Yan L, Zhang G, Liu J, Zhang F; Dapsone Hypersensitivity Syndrome Prevention Working Group; Xiong L, Yang J, Li J, Ke W, Li M, Ning Y, Xiong J, Li M, Xiong M, Yang B, Duan Q, Wang H, Li W, Kuang Y, Li J, Wang L, Cao Q, Xiao P, Xiao B, Zhang L, Lin Z, Wang Y, Shen Y, Yan L, Wu W, Zheng H, Zhan X, Li W, Shang X, Xu Y, Liu Q. Liu H, et al. Among authors: irwanto a. JAMA Dermatol. 2019 Jun 1;155(6):666-672. doi: 10.1001/jamadermatol.2018.5360. JAMA Dermatol. 2019. PMID: 30916737 Free PMC article.
Identification of IL18RAP/IL18R1 and IL12B as leprosy risk genes demonstrates shared pathogenesis between inflammation and infectious diseases.
Liu H, Irwanto A, Tian H, Fu X, Yu Y, Yu G, Low H, Chu T, Li Y, Shi B, Chen M, Sun Y, Yuan C, Lu N, You J, Bao F, Li J, Liu J, Liu H, Liu D, Yu X, Zhang L, Yang Q, Wang N, Niu G, Ma S, Zhou Y, Wang C, Chen S, Zhang X, Liu J, Zhang F. Liu H, et al. Among authors: irwanto a. Am J Hum Genet. 2012 Nov 2;91(5):935-41. doi: 10.1016/j.ajhg.2012.09.010. Epub 2012 Oct 25. Am J Hum Genet. 2012. PMID: 23103228 Free PMC article.
Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy.
Sun Y, Irwanto A, Toyo-Oka L, Hong M, Liu H, Andiappan AK, Choi H, Hitomi Y, Yu G, Yu Y, Bao F, Wang C, Fu X, Yue Z, Wang H, Zhang H, Kawashima M, Kojima K, Nagasaki M, Nakamura M, Yang SK, Ye BD, Denise Y, Rotzschke O, Song K, Tokunaga K, Zhang F, Liu J. Sun Y, et al. Among authors: irwanto a. Sci Rep. 2016 Aug 10;6:31429. doi: 10.1038/srep31429. Sci Rep. 2016. PMID: 27507062 Free PMC article.
HLA-B*13:01 and the dapsone hypersensitivity syndrome.
Zhang FR, Liu H, Irwanto A, Fu XA, Li Y, Yu GQ, Yu YX, Chen MF, Low HQ, Li JH, Bao FF, Foo JN, Bei JX, Jia XM, Liu J, Liany H, Wang N, Niu GY, Wang ZZ, Shi BQ, Tian HQ, Liu HX, Ma SS, Zhou Y, You JB, Yang Q, Wang C, Chu TS, Liu DC, Yu XL, Sun YH, Ning Y, Wei ZH, Chen SL, Chen XC, Zhang ZX, Liu YX, Pulit SL, Wu WB, Zheng ZY, Yang RD, Long H, Liu ZS, Wang JQ, Li M, Zhang LH, Wang H, Wang LM, Xiao P, Li JL, Huang ZM, Huang JX, Li Z, Liu J, Xiong L, Yang J, Wang XD, Yu DB, Lu XM, Zhou GZ, Yan LB, Shen JP, Zhang GC, Zeng YX, de Bakker PI, Chen SM, Liu JJ. Zhang FR, et al. Among authors: irwanto a. N Engl J Med. 2013 Oct 24;369(17):1620-8. doi: 10.1056/NEJMoa1213096. N Engl J Med. 2013. PMID: 24152261 Free article.
A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis.
Jin P, Andiappan AK, Quek JM, Lee B, Au B, Sio YY, Irwanto A, Schurmann C, Grabe HJ, Suri BK, Matta SA, Westra HJ, Franke L, Esko T, Sun L, Zhang X, Liu H, Zhang F, Larbi A, Xu X, Poidinger M, Liu J, Chew FT, Rotzschke O, Shi L, Wang de Y. Jin P, et al. Among authors: irwanto a. J Allergy Clin Immunol. 2015 Jun;135(6):1486-93.e8. doi: 10.1016/j.jaci.2014.12.1870. Epub 2015 Jan 30. J Allergy Clin Immunol. 2015. PMID: 25649076
43 results