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Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma.
Herviou L, Ovejero S, Izard F, Karmous-Gadacha O, Gourzones C, Bellanger C, De Smedt E, Ma A, Vincent L, Cartron G, Jin J, De Bruyne E, Grimaud C, Julien E, Moreaux J. Herviou L, et al. Among authors: izard f. Clin Epigenetics. 2021 Sep 16;13(1):174. doi: 10.1186/s13148-021-01160-z. Clin Epigenetics. 2021. PMID: 34530900 Free PMC article.
Structures of Nahuoic Acids B-E Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment and Evidence for the Inhibition of the Histone Methyl Transferase SETD8 in Human Cancer Cells by Nahuoic Acid A.
Williams DE, Izard F, Arnould S, Dalisay DS, Tantapakul C, Maneerat W, Matainaho T, Julien E, Andersen RJ. Williams DE, et al. Among authors: izard f. J Org Chem. 2016 Feb 19;81(4):1324-32. doi: 10.1021/acs.joc.5b02569. Epub 2016 Feb 1. J Org Chem. 2016. PMID: 26815947
Foci of cyclin A2 interact with actin and RhoA in mitosis.
Loukil A, Izard F, Georgieva M, Mashayekhan S, Blanchard JM, Parmeggiani A, Peter M. Loukil A, et al. Among authors: izard f. Sci Rep. 2016 Jun 9;6:27215. doi: 10.1038/srep27215. Sci Rep. 2016. PMID: 27279564 Free PMC article.