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Histone H4K20 tri-methylation at late-firing origins ensures timely heterochromatin replication.
EMBO J. 2017 Sep 15;36(18):2726-2741. doi: 10.15252/embj.201796541. Epub 2017 Aug 4.
EMBO J. 2017.
PMID: 28778956
Free PMC article.
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing.
Shoaib M, Walter D, Gillespie PJ, Izard F, Fahrenkrog B, Lleres D, Lerdrup M, Johansen JV, Hansen K, Julien E, Blow JJ, Sørensen CS.
Shoaib M, et al. Among authors: izard f.
Nat Commun. 2018 Sep 12;9(1):3704. doi: 10.1038/s41467-018-06066-8.
Nat Commun. 2018.
PMID: 30209253
Free PMC article.
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Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma.
Herviou L, Ovejero S, Izard F, Karmous-Gadacha O, Gourzones C, Bellanger C, De Smedt E, Ma A, Vincent L, Cartron G, Jin J, De Bruyne E, Grimaud C, Julien E, Moreaux J.
Herviou L, et al. Among authors: izard f.
Clin Epigenetics. 2021 Sep 16;13(1):174. doi: 10.1186/s13148-021-01160-z.
Clin Epigenetics. 2021.
PMID: 34530900
Free PMC article.
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Structures of Nahuoic Acids B-E Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment and Evidence for the Inhibition of the Histone Methyl Transferase SETD8 in Human Cancer Cells by Nahuoic Acid A.
Williams DE, Izard F, Arnould S, Dalisay DS, Tantapakul C, Maneerat W, Matainaho T, Julien E, Andersen RJ.
Williams DE, et al. Among authors: izard f.
J Org Chem. 2016 Feb 19;81(4):1324-32. doi: 10.1021/acs.joc.5b02569. Epub 2016 Feb 1.
J Org Chem. 2016.
PMID: 26815947
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Foci of cyclin A2 interact with actin and RhoA in mitosis.
Loukil A, Izard F, Georgieva M, Mashayekhan S, Blanchard JM, Parmeggiani A, Peter M.
Loukil A, et al. Among authors: izard f.
Sci Rep. 2016 Jun 9;6:27215. doi: 10.1038/srep27215.
Sci Rep. 2016.
PMID: 27279564
Free PMC article.
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