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International open-label studies to assess the efficacy and safety of single-pill amlodipine/atorvastatin in attaining blood pressure and lipid targets recommended by country-specific guidelines: the JEWEL programme.
Richard Hobbs FD, Gensini G, John Mancini GB, Manolis AJ, Bauer B, Genest J, Feldman RD, Harvey P, Jenssen TG, da Silva PM; JEWEL Study Group. Richard Hobbs FD, et al. Eur J Cardiovasc Prev Rehabil. 2009 Aug;16(4):472-80. doi: 10.1097/HJR.0b013e32832b63f5. Eur J Cardiovasc Prev Rehabil. 2009. PMID: 19407658 Clinical Trial.
Can combining different risk interventions into a single formulation contribute to improved cardiovascular disease risk reduction? Rationale and design for an international, open-label program to assess the effectiveness of a single pill (amlodipine/atorvastatin) to attain recommended target levels for blood pressure and lipids (The JEWEL Program).
Hobbs FD, Gensini G, Mancini GB, Manolis AJ, Bauer B, Böhler S, Genest J, Feldman R, Harvey P, Jenssen TG, Metcalfe M, da Silva PM; JEWEL Study Group. Hobbs FD, et al. Int J Cardiol. 2006 Jun 16;110(2):242-50. doi: 10.1016/j.ijcard.2005.10.017. Epub 2005 Dec 9. Int J Cardiol. 2006. PMID: 16338012